(Q53126778)

11 May 2018

title

Concise Synthesis of a Pateamine A Analogue with In Vivo Anticancer Activity Based on an Iron-Catalyzed Pyrone Ring Opening/Cross-Coupling. (English)

1 reference

11 May 2018

15-Amino-3-[7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trienyl]-9,11,17-trimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione

main subject

1 reference

1 reference

2

Alois Fürstner

1 reference

11 May 2018

Chun-Xiang Zhuo

1

1 reference

11 May 2018

language of work or name

English

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publication date

8 April 2016

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11 May 2018

Angewandte Chemie International Edition

number of pages

6

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based on heuristic

inferred from page(s)

published in

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volume

55

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11 May 2018

issue

20

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11 May 2018

page(s)

6051-6056

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11 May 2018

Homoharringtonine, omacetaxine mepesuccinate, and chronic myeloid leukemia circa 2009.

cites work

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Omacetaxine as an anticancer therapeutic: what is old is new again

21 January 2018

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Targeting the translation machinery in cancer

21 January 2018

1 reference

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Garbled messages and corrupted translations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Concise total synthesis of the potent translation and cell migration inhibitor lactimidomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Total syntheses and biological reassessment of lactimidomycin, isomigrastatin and congener glutarimide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Induction of apoptosis by the marine sponge (Mycale) metabolites, mycalamide A and pateamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Inhibition of eukaryotic translation initiation by the marine natural product pateamine A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Inhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIII

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Targeting the eIF4F translation initiation complex: a critical nexus for cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

The eIF4AIII RNA helicase is a critical determinant of human cytomegalovirus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Differential action of pateamine A on translation of genomic and subgenomic mRNAs from Sindbis virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

The cellular target specificity of pateamine A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Formal ring-opening/cross-coupling reactions of 2-pyrones: iron-catalyzed entry into stereodefined dienyl carboxylates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

The promise and challenge of iron-catalyzed cross coupling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Coming of age: sustainable iron-catalyzed cross-coupling reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Preparation, structure, and reactivity of nonstabilized organoiron compounds. Implications for iron-catalyzed cross coupling reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

On the reach of chemical synthesis: creation of a mini-pipeline from an academic laboratory

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Probing the biology of natural products: molecular editing by diverted total synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Scope and mechanism of the Pt-catalyzed enantioselective diboration of monosubstituted alkenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Catalytic Enantioselective Functionalization of Unactivated Terminal Alkenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Gold- or Silver-Catalyzed Syntheses of Pyrones and Pyridine Derivatives: Mechanistic and Synthetic Aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

From understanding to prediction: gold- and platinum-based π-acid catalysis for target oriented synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Catalytic carbophilic activation: catalysis by platinum and gold pi acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Gold and platinum catalysis--a convenient tool for generating molecular complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Dialkylbiaryl Phosphines in Pd-Catalyzed Amination: A User's Guide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Total synthesis of (+)-sorangicin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Macrolactonizations in the total synthesis of natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Sulfur trioxide in the oxidation of alcohols by dimethyl sulfoxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Synthesis, molecular editing, and biological assessment of the potent cytotoxin leiodermatolide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Molecular editing and assessment of the cytotoxic properties of iejimalide and progeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Simple and selective method for aldehydes (RCHO) .fwdarw. (E)-haloalkenes (RCH:CHX) conversion by means of a haloform-chromous chloride system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

A versatile protocol for Stille-Migita cross coupling reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Total syntheses of amphidinolides B1, B4, G1, H1 and structure revision of amphidinolide H2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Gram-scale synthesis of iejimalide B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

21 January 2018

The leiodolide B puzzle

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Redox economy in organic synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Synthesis at the molecular frontier

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Atom Economy—A Challenge for Organic Synthesis: Homogeneous Catalysis Leads the Way

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201602125

Directed ortho insertion (DoI): a new approach to functionalized aryl and heteroaryl zinc reagents

21 January 2018

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Total synthesis of neurymenolide A based on a gold-catalyzed synthesis of 4-hydroxy-2-pyrones

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Total syntheses of amphidinolide H and G

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

The Cellular Target Specificity of Pateamine A

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Unusual structure and reactivity of a homoleptic "super-ate" complex of iron: implications for Grignard additions, cross-coupling reactions, and the Kharasch deconjugation

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Total Synthesis of (±)-Mycothiazole and Formal Enantioselective Approach

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

RNA-Mediated Sequestration of the RNA Helicase eIF4A by Pateamine A Inhibits Translation Initiation

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Aquaculture trials for the production of biologically active metabolites in the New Zealand sponge Mycale hentscheli (Demospongiae: Poecilosclerida)

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis A list of abbreviations can be found at the end of the article

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Synthesis and evaluation of an Iejimalide-archazolid chimera

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Pateamine: a potent cytotoxin from the New Zealand Marine sponge, mycale sp.

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Total synthesis of an exceptional brominated 4-pyrone derivative of algal origin: an exercise in gold catalysis and alkyne metathesis

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Carbon−Carbon Bond Formations Involving Organochromium(III) Reagents

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Iron catalysis in organic synthesis

1 reference

9 March 2024

https://opencitations.net/index/api/v1/references/10.1002/ANIE.201602125

Identifiers

DOI

10.1002/ANIE.201602125

1 reference

11 May 2018

1 reference

11 May 2018