(Q53130070)

English

ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells.

scientific article published on 11 December 2012

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23228968%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells (English)

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Europe PubMed Central

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20 February 2020

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20 February 2020

Louise E Purton

3

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20 February 2020

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L C Y Chee

1

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20 February 2020

J Hendy

2

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20 February 2020

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11 December 2012

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20 February 2020

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20 February 2020

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20 February 2020

6

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20 February 2020

1369-1380

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20 February 2020

https://scigraph.springernature.com/pub.10.1038/leu.2012.362

0 references

Retinoic acid-induced granulocytic differentiation of HL-60 myeloid leukemia cells is mediated directly through the retinoic acid receptor (RAR-alpha).

1 reference

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21 January 2018

Multiple members of the retinoic acid receptor family are capable of mediating the granulocytic differentiation of HL-60 cells

1 reference

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21 January 2018

Lineage restriction of the RARalpha gene expression in myeloid differentiation

1 reference

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21 January 2018

RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation

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21 January 2018

The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: ...

1 reference

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21 January 2018

DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia

1 reference

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21 January 2018

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

1 reference

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21 January 2018

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

1 reference

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21 January 2018

AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

1 reference

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21 January 2018

Molecular genetics of human leukemias: new insights into therapy

1 reference

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Deletion of an AML1-ETO C-terminal NcoR/SMRT-interacting region strongly induces leukemia development

1 reference

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21 January 2018

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

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Summaries of Affymetrix GeneChip probe level data

1 reference

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21 January 2018

affy--analysis of Affymetrix GeneChip data at the probe level

1 reference

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21 January 2018

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.362

21 January 2018

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

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Synthesis and biological activity of retinoic acid receptor-alpha specific amides

1 reference

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Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

1 reference

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21 January 2018

HOXB4-induced expansion of adult hematopoietic stem cells ex vivo.

1 reference

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21 January 2018

Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression

1 reference

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21 January 2018

Retinoic acid receptors beta and gamma do not repress, but instead activate target gene transcription in both the absence and presence of hormone ligand

1 reference

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21 January 2018

Molecular mechanisms of mTOR-mediated translational control

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21 January 2018

The role of the nuclear Akt activation and Akt inhibitors in all-trans-retinoic acid-differentiated HL-60 cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.362

21 January 2018

Combined effect of retinoic acid and basic FGF on PAI-1 gene expression in vascular smooth muscle cells

1 reference

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21 January 2018

Retinoids induce the PAI-1 gene expression through tyrosine kinase-dependent pathways in vascular smooth muscle cells

1 reference

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21 January 2018

The urokinase plasminogen activator system: role in malignancy

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Cancer invasion and metastasis: changing views.

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The plasminogen activator inhibitor "paradox" in cancer

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Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1.

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The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro

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The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.

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JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

1 reference

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Bone morphogenetic proteins

1 reference

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Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism

1 reference

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21 January 2018

Granulocyte colony-stimulating factor and an RARalpha specific agonist, VTP195183, synergize to enhance the mobilization of hematopoietic progenitor cells

1 reference

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7 January 2021

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