(Q53154278)

English

Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer.

scientific article published on 28 July 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

colorectal cancer

1 reference

based on heuristic

inferred from title

inflammasome complex

1 reference

based on heuristic

inferred from title

genetic variation

1 reference

based on heuristic

inferred from title

author name string

Jonas Ungerbäck

1

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Dimitri Belenki

2

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Aksa Jawad ul-Hassan

3

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Mats Fredrikson

4

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Karin Fransén

5

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Nils Elander

6

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Deepti Verma

7

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Peter Söderkvist

8

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

language of work or name

0 references

publication date

28 July 2012

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

33

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

11

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

2126-2134

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

Hallmarks of Cancer: The Next Generation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

New insights into the aetiology of colorectal cancer from genome-wide association studies

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Inflammation and colon cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Colon carcinogenesis: Learning from NF-kappaB and AP-1.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

A20: from ubiquitin editing to tumour suppression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Impact of Toll-like receptor 4 polymorphisms on risk of cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Toll-like receptors and cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Expression, biological activities and mechanisms of action of A20 (TNFAIP3).

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

A20 RNA expression is associated with undifferentiated nasopharyngeal carcinoma and poorly differentiated head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

A20/TNFAIP3, a new estrogen-regulated gene that confers tamoxifen resistance in breast cancer cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Targeting A20 decreases glioma stem cell survival and tumor growth

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

A20 takes on tumors: tumor suppression by an ubiquitin-editing enzyme

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Rheumatoid arthritis association at 6q23.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Flat and polypoid adenocarcinomas of the colorectum: A comparative histomorphologic analysis of 47 cases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Comprehensive analysis of copy number and allele status identifies multiple chromosome defects underlying follicular lymphoma pathogenesis.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

NF-kB and Bcl-3 activation are prognostic in metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Allelotyping, microsatellite instability, and BRAF mutation analyses in common and atypical melanocytic nevi and primary cutaneous melanomas

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS256

21 January 2018

Identifiers

10.1093/CARCIN/BGS256

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22843550

ResearchGate publication ID

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