(Q53156735)

English

The prostate cancer blocking potential of the histone deacetylase inhibitor LBH589 is not enhanced by the multi receptor tyrosine kinase inhibitor TKI258.

scientific article published on 17 July 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

The prostate cancer blocking potential of the histone deacetylase inhibitor LBH589 is not enhanced by the multi receptor tyrosine kinase inhibitor TKI258. (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Roman A Blaheta

9

object named as

Roman A Blaheta

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

author name string

Stefan Vallo

1

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Jens Mani

2

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Matthias Stastny

3

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Jasmina Makarević

4

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Eva Juengel

5

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Igor Tsaur

6

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Georg Bartsch

7

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Axel Haferkamp

8

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

publication date

17 July 2012

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

31

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

2

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

265-272

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

Global cancer statistics

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Cancer statistics, 2009

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Therapeutic options in androgen-independent prostate cancer: building on docetaxel

1 reference

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21 January 2018

Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients : randomized phase 2 study of ixabepilone or mitoxantrone and prednisone.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Low dosed interferon alpha augments the anti-tumor potential of histone deacetylase inhibition on prostate cancer cell growth and invasion

1 reference

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21 January 2018

Involvement of HDAC1 in E-cadherin expression in prostate cancer cells; its implication for cell motility and invasion

1 reference

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21 January 2018

Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression

1 reference

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21 January 2018

Phase II study of sunitinib in men with advanced prostate cancer.

1 reference

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21 January 2018

A phase II study of lapatinib, a dual EGFR and HER-2 tyrosine kinase inhibitor, in patients with castration-resistant prostate cancer

1 reference

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21 January 2018

Dasatinib: an anti-tumour agent via Src inhibition

1 reference

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21 January 2018

Erlotinib has moderate single-agent activity in chemotherapy-naïve castration-resistant prostate cancer: final results of a phase II trial

1 reference

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21 January 2018

In vivo target modulation and biological activity of CHIR-258, a multitargeted growth factor receptor kinase inhibitor, in colon cancer models

1 reference

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21 January 2018

A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Preclinical evaluation of combined antineoplastic effect of DLC1 tumor suppressor protein and suberoylanilide hydroxamic acid on prostate cancer cells

1 reference

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21 January 2018

Depsipeptide (FK228) inhibits growth of human prostate cancer cells

1 reference

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21 January 2018

Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

MS-275 synergistically enhances the growth inhibitory effects of RAMBA VN/66-1 in hormone-insensitive PC-3 prostate cancer cells and tumours.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Improved synthesis of histone deacetylase inhibitors (HDIs) (MS-275 and CI-994) and inhibitory effects of HDIs alone or in combination with RAMBAs or retinoids on growth of human LNCaP prostate cancer cells and tumor xenografts

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: phase I/II trial of valproic acid and epirubicin/FEC.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Molecular aspects of gefitinib antiproliferative and pro-apoptotic effects in PTEN-positive and PTEN-negative prostate cancer cell lines.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Effects of EGFR tyrosine kinase inhibitor erlotinib in prostate cancer cells in vitro.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Modulation of Akt/mTOR signaling overcomes sunitinib resistance in renal and prostate cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Targeting fibroblast growth factor receptors blocks PI3K/AKT signaling, induces apoptosis, and impairs mammary tumor outgrowth and metastasis

1 reference

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21 January 2018

Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

Fibroblast growth factors and their receptors in cancer

1 reference

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21 January 2018

Bevacizumab/docetaxel association is more efficient than docetaxel alone in reducing breast and prostate cancer cell growth: a new paradigm for understanding the therapeutic effect of combined treatment

1 reference

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21 January 2018

Discovery of 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide (CUDc-101) as a potent multi-acting HDAC, EGFR, and HER2 inhibitor for the treatment of cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9851-5

21 January 2018

HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT.

1 reference

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21 January 2018

Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib

1 reference

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21 January 2018

Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells

1 reference

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21 January 2018

Effects of combined valproic acid and the epidermal growth factor/vascular endothelial growth factor receptor tyrosine kinase inhibitor AEE788 on renal cell carcinoma cell lines in vitro

1 reference

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21 January 2018

Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of PXD101 (belinostat) on androgen-dependent and androgen-independent prostate cancer models

1 reference

https://pubmed.ncbi.nlm.nih.gov/22801803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-012-9851-5

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 May 2018

http://europepmc.org/abstract/MED/22801803

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