(Q53178602)

12 May 2018

title

Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate. (English)

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12 May 2018

author

David Ron

4

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12 May 2018

Heather P Harding

object named as

Heather P Harding

2

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Stephen O'Rahilly

object named as

Stephen O'Rahilly

3

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Giles See How Yeo

5

object named as

Giles S H Yeo

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12 May 2018

author name string

Marcella Ma

1

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12 May 2018

language of work or name

English

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publication date

1 June 2012

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12 May 2018

published in

Biochemical Journal

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12 May 2018

volume

444

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12 May 2018

issue

2

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12 May 2018

page(s)

183-187

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12 May 2018

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

cites work

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

From GWAS to biology: lessons from FTO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Crystal structure of the FTO protein reveals basis for its substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Prevalence of loss-of-function FTO mutations in lean and obese individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Coulombic effects of remote subsites on the active site of ribonuclease A

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Endoribonuclease activity of human apurinic/apyrimidinic endonuclease 1 revealed by a real-time fluorometric assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Using molecular beacons as a sensitive fluorescence assay for enzymatic cleavage of single-stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Chimeric RNA-DNA molecular beacon assay for ribonuclease H activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Overexpression of Fto leads to increased food intake and results in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Inactivation of the Fto gene protects from obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Effects of alpha-ketoglutarate on neutrophil intracellular amino and alpha-keto acid profiles and ROS production

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

A novel method for the determination of post-transcriptional modification in RNA by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

A Residue to Residue Hydrogen Bond Mediates the Nucleotide Specificity of Ribonuclease A

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20120065

21 January 2018

Identifiers

DOI

10.1042/BJ20120065

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12 May 2018

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12 May 2018