(Q53210386)

12 May 2018

title

EDA Fibronectin in Keloids Create a Vicious Cycle of Fibrotic Tumor Formation. (English)

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12 May 2018

author name string

Rhiannon M Kelsh

series ordinal

1

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12 May 2018

Paula J McKeown-Longo

series ordinal

2

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12 May 2018

Richard A F Clark

series ordinal

3

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12 May 2018

language of work or name

English

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publication date

1 July 2015

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12 May 2018

Journal of Investigative Dermatology

published in

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12 May 2018

volume

135

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12 May 2018

issue

7

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12 May 2018

page(s)

1714-1718

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/jid.2015.155

exact match

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cites work

The α4β1 integrin and the EDA domain of fibronectin regulate a profibrotic phenotype in dermal fibroblasts

1 reference

12 December 2020

Keloid fibroblasts exhibit an altered response to TGF-beta

1 reference

12 December 2020

Partial primary structure of bovine plasma fibronectin: Three types of internal homology

1 reference

12 December 2020

Hepatocyte growth Factor/Scatter factor (HGF/SF) is a regulator of fibronectin splicing in MDCK cells: comparison between the effects of HGF/SF and TGF-beta1 on fibronectin splicing at the EDA region

1 reference

12 December 2020

Fibronectin synthesis in tubular epithelial cells: up-regulation of the EDA splice variant by transforming growth factor beta

1 reference

12 December 2020

Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat.

1 reference

12 December 2020

Rat alveolar myofibroblasts acquire alpha-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis

1 reference

12 December 2020

The EDA-containing cellular fibronectin induces epithelial-mesenchymal transition in lung cancer cells through integrin α9β1-mediated activation of PI3-K/AKT and Erk1/2.

1 reference

12 December 2020

The spatial and temporal expression patterns of integrin alpha9beta1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing

1 reference

12 December 2020

Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat

1 reference

12 December 2020

Type III and V collagens modulate the expression and assembly of EDA(+) fibronectin in the extracellular matrix of defective Ehlers-Danlos syndrome fibroblasts.

1 reference

12 December 2020

Influence of RNA secondary structure on the pre-mRNA splicing process

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12 December 2020

Transforming growth factor-beta regulates the splicing pattern of fibronectin messenger RNA precursor

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12 December 2020

Mammary epithelial-mesenchymal interaction regulates fibronectin alternative splicing via phosphatidylinositol 3-kinase.

1 reference

12 December 2020

Deletion of the alternatively spliced fibronectin EIIIA domain in mice reduces atherosclerosis

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12 December 2020

Recipient-derived EDA fibronectin promotes cardiac allograft fibrosis

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12 December 2020

Transforming growth factor beta regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts

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12 December 2020

Changes in plasma fibronectin isoform levels predict distinct clinical outcomes in critically ill patients

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12 December 2020

Fibronectin at select sites binds multiple growth factors and enhances their activity: expansion of the collaborative ECM-GF paradigm

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12 December 2020

Complex epithelial-mesenchymal interactions modulate transforming growth factor-beta expression in keloid-derived cells

1 reference

12 December 2020

Keloid-derived fibroblasts are refractory to Fas-mediated apoptosis and neutralization of autocrine transforming growth factor-beta1 can abrogate this resistance

1 reference

12 December 2020

EDA-containing cellular fibronectin induces fibroblast differentiation through binding to alpha4beta7 integrin receptor and MAPK/Erk 1/2-dependent signaling

1 reference

12 December 2020

Morphological and immunochemical differences between keloid and hypertrophic scar

1 reference

12 December 2020

Extra-domain-A fibronectin: a new marker of fibrosis in cutaneous graft-versus-host disease

1 reference

12 December 2020

Functional association between promoter structure and transcript alternative splicing.

1 reference

12 December 2020

Fibronectins, their fibrillogenesis, and in vivo functions

1 reference

12 December 2020

The extra domain A of fibronectin is essential for allergen-induced airway fibrosis and hyperresponsiveness in mice

1 reference

12 December 2020

Temporal relationships of F-actin bundle formation, collagen and fibronectin matrix assembly, and fibronectin receptor expression to wound contraction

1 reference

12 December 2020

Phosphorylation-mediated regulation of alternative splicing in cancer

1 reference

12 December 2020

Hypertrophic scar fibroblasts have increased connective tissue growth factor expression after transforming growth factor-beta stimulation

1 reference

12 December 2020

Toll-like receptor 4 signaling augments transforming growth factor-β responses: a novel mechanism for maintaining and amplifying fibrosis in scleroderma

1 reference

12 December 2020

The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing.

1 reference

12 December 2020

Patterns of alternative splicing of fibronectin pre-mRNA in human adult and fetal tissues

1 reference

12 December 2020

Differential expression of the ED sequence-containing form of cellular fibronectin in embryonic and adult human tissues

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12 December 2020

The extra domain A of fibronectin activates Toll-like receptor 4.

1 reference

12 December 2020

Improving cutaneous scar formation by controlling the mechanical environment: large animal and phase I studies

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12 December 2020

Extra domain A-positive fibronectin-positive feedback loops and their association with cutaneous inflammatory disease

1 reference

12 December 2020

The extra domain A from fibronectin targets antigens to TLR4-expressing cells and induces cytotoxic T cell responses in vivo

1 reference

12 December 2020

Regulation of fibronectin alternative splicing by a basement membrane-like extracellular matrix.

1 reference

12 December 2020

Upregulation of TGF-β1 Expression May Be Necessary but Is Not Sufficient for Excessive Scarring

1 reference

12 December 2020

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1 reference

12 December 2020

The extra domain A of fibronectin stimulates murine mast cells via toll-like receptor 4

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12 December 2020

TGF-beta signaling and the fibrotic response

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12 December 2020

Regulation of wound healing and organ fibrosis by toll-like receptors.

1 reference

12 December 2020

The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors

1 reference

12 December 2020

Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway

1 reference

12 December 2020

The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1.

1 reference

12 December 2020

Fibronectin provides a conduit for fibroblast transmigration from collagenous stroma into fibrin clot provisional matrix

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12 December 2020

An essential role for fibronectin extra type III domain A in pulmonary fibrosis.

1 reference

12 December 2020

Cellular fibronectin is induced by epidermal growth factor, but not by dexamethasone or cyclic AMP in rat liver epithelial cells

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12 December 2020

Increased extra domain-A containing fibronectin and hepatic dysfunction during septic response: an in vivo and in vitro study

1 reference

12 December 2020

Elevated plasma levels of ED1+ ("cellular") fibronectin in patients with vascular injury

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12 December 2020

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

1 reference

12 December 2020

The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis

1 reference

12 December 2020

Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.

1 reference

12 December 2020

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding

1 reference

12 December 2020

Kinetics of endogenously labeled plasma fibronectin: incorporation into tissues.

1 reference

12 December 2020

Keloid Pathogenesis: Potential Role of Cellular Fibronectin with the EDA Domain

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12 December 2020

Reduced growth-factor requirement of keloid-derived fibroblasts may account for tumor growth

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12 December 2020

Regulation of the innate immune response by fibronectin: synergism between the III-1 and EDA domains

1 reference

12 December 2020

Lack of Fibronectin-EDA Promotes Survival and Prevents Adverse Remodeling and Heart Function Deterioration After Myocardial Infarction

1 reference

12 December 2020

Identification of the peptide sequences within the EIIIA (EDA) segment of fibronectin that mediate integrin alpha9beta1-dependent cellular activities.

1 reference

12 December 2020

FibronectinEDA promotes chronic cutaneous fibrosis through Toll-like receptor signaling.

1 reference

12 December 2020

Identifiers

DOI

10.1038/JID.2015.155

1 reference

12 May 2018

1 reference

12 May 2018