(Q53222824)

12 May 2018

title

Chromosomal breaks during mitotic catastrophe trigger γH2AX-ATM-p53-mediated apoptosis. (English)

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12 May 2018

author

Boris Zhivotovsky

4

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12 May 2018

author name string

Gabriela Imreh

1

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12 May 2018

Helin Vakifahmetoglu Norberg

2

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12 May 2018

Stefan Imreh

3

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12 May 2018

language of work or name

English

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publication date

1 September 2011

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12 May 2018

published in

Journal of Cell Science

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12 May 2018

volume

124

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12 May 2018

issue

Pt 17

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12 May 2018

page(s)

2951-2963

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12 May 2018

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

cites work

1 reference

https://api.crossref.org/works/10.1242%2FJCS.081612

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

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Apoptosis regulation in tetraploid cancer cells

21 January 2018

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Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

21 January 2018

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The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe

21 January 2018

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14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

21 January 2018

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Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

21 January 2018

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Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype

21 January 2018

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Mitotic catastrophe and endomitosis in tumour cells: an evolutionary key to a molecular solution.

21 January 2018

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H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis

21 January 2018

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

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DNA damage signaling in response to double-strand breaks during mitosis

21 January 2018

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Mitochondrial dysfunction is an early indicator of doxorubicin-induced apoptosis

21 January 2018

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Mitotic catastrophe is the predominant response to histone acetyltransferase depletion

21 January 2018

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Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint

21 January 2018

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DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint

21 January 2018

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Phosphorylation of histone H2AX at M phase in human cells without DNA damage response

21 January 2018

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The many substrates and functions of ATM

21 January 2018

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In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide

21 January 2018

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Sustained metaphase arrest in response to ionizing radiation in a non-small cell lung cancer cell line

21 January 2018

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Structure meets function--centrosomes, genome maintenance and the DNA damage response

21 January 2018

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Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe

21 January 2018

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BUB1 mediation of caspase-independent mitotic death determines cell fate

21 January 2018

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DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis

21 January 2018

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Cdc2 and Cdk2 play critical roles in low dose doxorubicin-induced cell death through mitotic catastrophe but not in high dose doxorubicin-induced apoptosis

21 January 2018

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Bcl-xL blocks high dose doxorubicin-induced apoptosis but not low dose doxorubicin-induced cell death through mitotic catastrophe

21 January 2018

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Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-strand breakage

21 January 2018

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If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

21 January 2018

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Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability

21 January 2018

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In vivo genotoxicity of ortho-phenylphenol, biphenyl, and thiabendazole detected in multiple mouse organs by the alkaline single cell gel electrophoresis assay

21 January 2018

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Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro

21 January 2018

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The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

21 January 2018

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An essential role for p73 in regulating mitotic cell death

21 January 2018

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Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage

21 January 2018

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DNA damage induces two distinct modes of cell death in ovarian carcinomas

21 January 2018

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Caspase-independent apoptosis is activated by diazepam-induced mitotic failure in HeLa cells, but not in human primary fibroblasts

21 January 2018

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

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Chromosomes of X-ray-induced Giant Cells in Chinese Hamster in vitro

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1242/JCS.081612

1 reference

12 May 2018

1 reference

12 May 2018