(Q53226362)

12 May 2018

title

C-terminal mutation of RUNX1 attenuates the DNA-damage repair response in hematopoietic stem cells. (English)

1 reference

12 May 2018

author name string

Y Satoh

1

1 reference

12 May 2018

I Matsumura

2

1 reference

12 May 2018

H Tanaka

3

1 reference

12 May 2018

H Harada

4

1 reference

12 May 2018

Y Harada

5

1 reference

12 May 2018

K Matsui

6

1 reference

12 May 2018

M Shibata

7

1 reference

12 May 2018

M Mizuki

8

1 reference

12 May 2018

Y Kanakura

9

1 reference

12 May 2018

publication date

12 August 2011

1 reference

12 May 2018

published in

Leukemia

1 reference

12 May 2018

volume

26

1 reference

12 May 2018

issue

2

1 reference

12 May 2018

page(s)

303-311

1 reference

12 May 2018

https://scigraph.springernature.com/pub.10.1038/leu.2011.202

exact match

0 references

cites work

Molecular mechanisms of myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Mutation in TET2 in myeloid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Core-binding factors in haematopoiesis and leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

The DNA-damage response in human biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Repair of endogenous DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Genome maintenance mechanisms for preventing cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Runx1 deficiency predisposes mice to T-lymphoblastic lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Gadd45 in stress signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Proposals for the classification of the myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

AML1/RUNX1 works as a negative regulator of c-Mpl in hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

gammaH2AX: a sensitive molecular marker of DNA damage and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Simultaneous establishment of monoclonal antibodies specific for either cyclobutane pyrimidine dimer or (6-4)photoproduct from the same mouse immunized with ultraviolet-irradiated DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Repression of Gadd45alpha by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

p53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Hematopoietic cells from Gadd45a- and Gadd45b-deficient mice are sensitized to genotoxic-stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

7 January 2021

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

7 January 2021

Genomic instability in Gadd45a-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

7 January 2021

Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

7 January 2021

Somatic point mutations in RUNX1/CBFA2/AML1 are common in high-risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

7 January 2021

RUNX1 gene mutation in primary myelodysplastic syndrome--the mutation can be detected early at diagnosis or acquired during disease progression and is associated with poor outcome

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.202

7 January 2021

Identifiers

DOI

10.1038/LEU.2011.202

1 reference

12 May 2018

1 reference

12 May 2018