(Q53231417)

English

The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons.

scientific article published in December 1999

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scholarly article

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons. (English)

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

Alzheimer's disease

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

author name string

M D Caswell

1

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

S S Mok

2

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

A Henry

3

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

G Klug

5

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

K Beyreuther

6

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

C L Masters

7

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

D H Small

8

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

language of work or name

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publication date

1 December 1999

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

number of pages

8

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inferred from page(s)

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

266

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

2

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Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

509-516

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

N-linked glycosylation of beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Beta-amyloid protein promotes neuritic branching in hippocampal cultures

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Expression of the amyloid protein precursor of Alzheimer's disease in the developing rat olfactory system.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Protease nexin-2/amyloid beta protein precursor. A tight-binding inhibitor of coagulation factor IXa.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Potential Role of Protease Nexin‐2/Amyloid β‐Protein Precursor as a Cerebral Anticoagulanta

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Cleavage of amyloid beta peptide during constitutive processing of its precursor

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Identification of a metalloprotease from Alzheimer's disease brain able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

A metalloproteinase inhibitor domain in Alzheimer amyloid protein precursor.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid beta-protein.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Coagulation factor XIa cleaves the RHDS sequence and abolishes the cell adhesive properties of the amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Proteolysis of Alzheimer's disease beta-amyloid precursor protein by factor Xa.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Post-translational processing and turnover kinetics of presynaptically targeted amyloid precursor superfamily proteins in the central nervous system.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Human brain beta A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Surface-specific iodination of membrane proteins of viruses and eucaryotic cells using 1,3,4,6-tetrachloro-3α,6α-diphenylglycoluril

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Regulation of amyloid precursor protein cleavage.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Calcium-Dependent Intracellular Degradation of Parathyroid Hormone: A Possible Mechanism for the Regulation of Hormone Stores12

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Intracellular degradation in the regulation of secretion of apolipoprotein B-100 by rabbit hepatocytes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Kunitz protease inhibitor-containing amyloid beta protein precursor immunoreactivity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Genetic association of the low-density lipoprotein receptor-related protein gene (LRP), an apolipoprotein E receptor, with late-onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Association at LRP gene locus with sporadic late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Inhibition of Protease Activity Can Lead to Neurite Extension in Neuroblastoma Cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Thrombin modulates and reverses neuroblastoma neurite outgrowth

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Intracellular routing of human amyloid protein precursor: Axonal delivery followed by transport to the dendrites

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1327.1999.00886.X

21 January 2018

Identifiers

10.1046/J.1432-1327.1999.00886.X

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/10561592

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