(Q53261745)

12 May 2018

title

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms. (English)

1 reference

12 May 2018

author

Zaklina Kovacevic

1

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12 May 2018

Des R. Richardson

6

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12 May 2018

author name string

Sutharshani Sivagurunathan

2

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12 May 2018

Helena Mangs

3

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12 May 2018

Sherin Chikhani

4

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12 May 2018

Daohai Zhang

5

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12 May 2018

language of work or name

English

0 references

publication date

11 March 2011

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12 May 2018

published in

Carcinogenesis

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12 May 2018

volume

32

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12 May 2018

issue

5

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12 May 2018

page(s)

732-740

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12 May 2018

Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression.

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The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.

21 January 2018

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Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis

21 January 2018

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NDRG1 is necessary for p53-dependent apoptosis

21 January 2018

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Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes

21 January 2018

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The iron-regulated metastasis suppressor, Ndrg-1: identification of novel molecular targets

21 January 2018

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Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation

21 January 2018

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Novel di-2-pyridyl-derived iron chelators with marked and selective antitumor activity: in vitro and in vivo assessment.

21 January 2018

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A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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p21 in cancer: intricate networks and multiple activities

21 January 2018

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A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis

21 January 2018

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Loss of nuclear p21(Cip1/WAF1) during neoplastic progression to metastasis in gamma-irradiated p21 hemizygous mice

21 January 2018

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MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation

21 January 2018

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NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states

21 January 2018

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Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1.

21 January 2018

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The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: The mechanisms involved in inhibiting cell-cycle progression

21 January 2018

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Iron chelation and regulation of the cell cycle: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion

21 January 2018

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The effect of potent iron chelators on the regulation of p53: examination of the expression, localization and DNA-binding activity of p53 and the transactivation of WAF1.

21 January 2018

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The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis.

21 January 2018

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Cytokeratin 19 regulates endoplasmic reticulum stress and inhibits ERp29 expression via p38 MAPK/XBP-1 signaling in breast cancer cells

21 January 2018

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The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin

21 January 2018

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Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3

21 January 2018

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N-myc downregulated gene 1 is a phosphorylated protein in mast cells

21 January 2018

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Molecular characterization of human prostate carcinoma cell lines

21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

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DNA-binding and transactivation activities are essential for TAp63 protein degradation.

21 January 2018

1 reference

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Alternative and aberrant splicing of MDM2 mRNA in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate.

21 January 2018

1 reference

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Metastasis suppressor genes: from gene identification to protein function and regulation

21 January 2018

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MMP9 potentiates pulmonary metastasis formation

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

The chemokine system -- a major regulator of angiogenesis in health and disease

21 January 2018

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Subcellular localization of Nm23/NDPK A and B isoforms: a reflection of their biological function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

Assessing TP53 status in human tumours to evaluate clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

p21-containing cyclin kinases exist in both active and inactive states

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

Cyclin D1/cyclin-dependent kinase 4 interacts with filamin A and affects the migration and invasion potential of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGR046

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGR046

1 reference

12 May 2018

PubMed ID

21398495

1 reference

12 May 2018