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Alternative and aberrant splicing of MDM2 mRNA in human cancer
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
review article
1 reference
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Europe PubMed Central
title
Alternative and aberrant splicing of MDM2 mRNA in human cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
author
Helge Taubert
object named as
Helge Taubert
series ordinal
2
0 references
author name string
Frank Bartel
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
Linda C Harris
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
publication date
1 July 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
published in
Cancer Cell
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
volume
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
page(s)
9-15
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Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
cites work
The contribution of the acidic domain of MDM2 to p53 and MDM2 stability
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7 January 2021
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Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential
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Amplification of the MDM2 gene, but not expression of splice variants of MDM2 MRNA, is associated with prognosis in soft tissue sarcoma
1 reference
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https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Novel mdm2 splice variants identified in pediatric rhabdomyosarcoma tumors and cell lines
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis
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https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Role of two upstream open reading frames in the translational control of oncogene mdm2.
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7 January 2021
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inferred from DOI database lookup
Abnormal expression of MDM-2 in breast carcinomas
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7 January 2021
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Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
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https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
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https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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An alternatively spliced HDM2 product increases p53 activity by inhibiting HDM2
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila.
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Functions of the MDM2 oncoprotein
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Overexpression of MDM2 in acute childhood lymphoblastic leukemia
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reference URL
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7 January 2021
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Physical and functional interaction between wild-type p53 and mdm2 proteins
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Alternatively spliced MDM2 transcripts in human breast cancer in relation to tumor necrosis and lymph node involvement.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
retrieved
7 January 2021
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inferred from DOI database lookup
Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of alternatively spliced mdm2 transcripts correlates with stabilized wild-type p53 protein in human glioblastoma cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Regulation of p53 stability by Mdm2
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Loss of MDM2 expression in human head and neck squamous cell carcinomas and clinical significance
1 reference
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https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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The MDM2 gene amplification database
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Crossref
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https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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MDM2--master regulator of the p53 tumor suppressor protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
The organization and expression of the mdm2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of a gene encoding a p53-associated protein in human sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2: keeping p53 under control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of MDM2 during mammary tumorigenesis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
Genetic analysis of the human oncoprotein MDM2 in benign and malignant tumors of the salivary gland
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor surveillance via the ARF-p53 pathway.
1 reference
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https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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inferred from DOI database lookup
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
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Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel exon within the mdm2 gene modulates translation initiation in vitro and disrupts the p53-binding domain of mdm2 protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The p53-mdm-2 autoregulatory feedback loop
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
A functional p53-responsive intronic promoter is contained within the human mdm2 gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Mdm2 mutant defective in binding p300 promotes ubiquitination but not degradation of p53: evidence for the role of p300 in integrating ubiquitination and proteolysis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0
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7 January 2021
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Identifiers
DOI
10.1016/S1535-6108(02)00091-0
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
PubMed ID
12150820
1 reference
stated in
Europe PubMed Central
PubMed ID
12150820
retrieved
4 August 2017
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