(Q34768629)

4 August 2017

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title

Alternative and aberrant splicing of MDM2 mRNA in human cancer (English)

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4 August 2017

Helge Taubert

2

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author name string

Frank Bartel

series ordinal

1

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4 August 2017

Linda C Harris

series ordinal

3

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4 August 2017

publication date

1 July 2002

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4 August 2017

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4 August 2017

volume

2

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4 August 2017

issue

1

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4 August 2017

page(s)

9-15

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The contribution of the acidic domain of MDM2 to p53 and MDM2 stability

4 August 2017

cites work

1 reference

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7 January 2021

Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

1 reference

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7 January 2021

Amplification of the MDM2 gene, but not expression of splice variants of MDM2 MRNA, is associated with prognosis in soft tissue sarcoma

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7 January 2021

Novel mdm2 splice variants identified in pediatric rhabdomyosarcoma tumors and cell lines

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7 January 2021

The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis

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7 January 2021

Role of two upstream open reading frames in the translational control of oncogene mdm2.

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7 January 2021

Abnormal expression of MDM-2 in breast carcinomas

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7 January 2021

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

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7 January 2021

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

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7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

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7 January 2021

An alternatively spliced HDM2 product increases p53 activity by inhibiting HDM2

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7 January 2021

Overexpression of mouse Mdm2 induces developmental phenotypes in Drosophila.

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7 January 2021

Functions of the MDM2 oncoprotein

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7 January 2021

Overexpression of MDM2 in acute childhood lymphoblastic leukemia

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7 January 2021

Physical and functional interaction between wild-type p53 and mdm2 proteins

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7 January 2021

MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation

1 reference

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7 January 2021

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

1 reference

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7 January 2021

Alternatively spliced MDM2 transcripts in human breast cancer in relation to tumor necrosis and lymph node involvement.

1 reference

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7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

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7 January 2021

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

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7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

1 reference

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7 January 2021

Expression of alternatively spliced mdm2 transcripts correlates with stabilized wild-type p53 protein in human glioblastoma cells

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Loss of MDM2 expression in human head and neck squamous cell carcinomas and clinical significance

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7 January 2021

The MDM2 gene amplification database

1 reference

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7 January 2021

MDM2--master regulator of the p53 tumor suppressor protein

1 reference

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

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7 January 2021

Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes

1 reference

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7 January 2021

The organization and expression of the mdm2 gene

1 reference

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7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

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7 January 2021

Mdm2: keeping p53 under control

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7 January 2021

Expression of MDM2 during mammary tumorigenesis.

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7 January 2021

Genetic analysis of the human oncoprotein MDM2 in benign and malignant tumors of the salivary gland

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7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

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7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

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7 January 2021

Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

1 reference

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7 January 2021

Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas

1 reference

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7 January 2021

A novel exon within the mdm2 gene modulates translation initiation in vitro and disrupts the p53-binding domain of mdm2 protein

1 reference

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7 January 2021

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

1 reference

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7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

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7 January 2021

High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities

1 reference

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7 January 2021

Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes

1 reference

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7 January 2021

A functional p53-responsive intronic promoter is contained within the humanmdm2gene

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2802%2900091-0

7 January 2021

Mdm2 mutant defective in binding p300 promotes ubiquitination but not degradation of p53: evidence for the role of p300 in integrating ubiquitination and proteolysis

1 reference

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7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

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7 January 2021

10.1016/S1535-6108(02)00091-0

Identifiers

DOI

1 reference

4 August 2017

1 reference