(Q53275444)

12 May 2018

title

The heterodimerization domains of MLL-FYRN and FYRC--are potential target structures in t(4;11) leukemia. (English)

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12 May 2018

protein heterodimerization activity

main subject

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3

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12 May 2018

Roland Stauber

4

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12 May 2018

Theodor Dingermann

5

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12 May 2018

Rolf Marschalek

6

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12 May 2018

author name string

B Pless

1

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12 May 2018

C Oehm

2

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12 May 2018

publication date

14 January 2011

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12 May 2018

published in

Leukemia

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12 May 2018

volume

25

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12 May 2018

issue

4

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12 May 2018

page(s)

663-670

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/leu.2010.308

exact match

0 references

cites work

New insights to the MLL recombinome of acute leukemias

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Exon/intron structure of the human AF-4 gene, a member of the AF-4/LAF-4/FMR-2 gene family coding for a nuclear protein with structural alterations in acute leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4·MLL fusion allele

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Transcription linked to recombination: a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

A conditional model of MLL-AF4 B-cell tumourigenesis using invertor technology

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Interaction of AF4 wild-type and AF4.MLL fusion protein with SIAH proteins: indication for t(4;11) pathobiology?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Systematic identification of novel protein domain families associated with nuclear functions

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

The structure of the FYR domain of transforming growth factor beta regulator 1

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

P-TEFb- the final frontier

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Controlling the elongation phase of transcription with P-TEFb

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Purification of P-TEFb, a transcription factor required for the transition into productive elongation.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Cell-based analysis of structure-function activity of threonine aspartase 1

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Development of an autofluorescent translocation biosensor system to investigate protein-protein interactions in living cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Genomic DNA of leukemic patients: Target for clinical diagnosis ofMLL rearrangements

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.308

7 January 2021

Identifiers

DOI

10.1038/LEU.2010.308

1 reference

12 May 2018

PubMed ID

21233834

1 reference

12 May 2018