(Q53288818)

13 May 2018

title

Single molecule profiling of tau gene expression in Alzheimer's disease. (English)

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13 May 2018

George Church

8

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Bradley Hyman

9

object named as

Bradley T Hyman

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13 May 2018

6

Martin Ingelsson

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13 May 2018

author name string

Chris Conrad

1

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13 May 2018

Jun Zhu

2

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13 May 2018

Cintia Conrad

3

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13 May 2018

David Schoenfeld

4

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13 May 2018

Zhide Fang

5

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13 May 2018

Stefan Stamm

7

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13 May 2018

language of work or name

English

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publication date

28 August 2007

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13 May 2018

Journal of Neurochemistry

published in

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13 May 2018

volume

103

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13 May 2018

issue

3

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13 May 2018

page(s)

1228-1236

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13 May 2018

Mathematical models of diffusion-constrained polymerase chain reactions: basis of high-throughput nucleic acid assays and simple self-organizing systems.

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Association of an extended haplotype in the tau gene with progressive supranuclear palsy

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Family-based association between Alzheimer's disease and variants in UBQLN1

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Expression of tau mRNA and soluble tau isoforms in affected and non-affected brain areas in Alzheimer's disease.

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Haplotype-specific expression of exon 10 at the human MAPT locus

21 January 2018

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Overexpression of four-repeat tau mRNA isoforms in progressive supranuclear palsy but not in Alzheimer's disease

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Quantitative analysis of tau isoform transcripts in sporadic tauopathies

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Molecular evolution and genetics of the Saitohin gene and tau haplotype in Alzheimer's disease and argyrophilic grain disease

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Regulation of tau isoform expression and dementia

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Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

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Increased frequency of argyrophilic grain disease in Alzheimer disease with 4R tau-specific immunohistochemistry.

21 January 2018

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Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

21 January 2018

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

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No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain

21 January 2018

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Neuritic alterations and neural system dysfunction in Alzheimer's disease and dementia with Lewy bodies

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Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies

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Initial sequencing and analysis of the human genome

21 January 2018

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Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes

21 January 2018

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Alternative pre-mRNA splicing and proteome expansion in metazoans

21 January 2018

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Expression of microtubule-associated proteins MAP2 and tau in cultured rat brain oligodendrocytes

21 January 2018

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The H1c haplotype at the MAPT locus is associated with Alzheimer's disease.

21 January 2018

1 reference

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The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Glial tau-positive structures lack the sequence encoded by exon 3 of the tau protein gene

21 January 2018

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The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells

21 January 2018

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cRNA target preparation for microarrays: comparison of gene expression profiles generated with different amplification procedures

21 January 2018

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Dysregulation of human brain microtubule-associated tau mRNA maturation in myotonic dystrophy type 1.

21 January 2018

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Accurate multiplex polony sequencing of an evolved bacterial genome

21 January 2018

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An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Expression patterns of tau mRNA isoforms correlate with susceptible lesions in progressive supranuclear palsy and corticobasal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Alterations in human tau transcripts correlate with those of neurofilament in sporadic tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Glial reaction in aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Tangled areas of Alzheimer brain have upregulated levels of exon 10 containing tau mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Single molecule profiling of alternative pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04857.X

10.1111/J.1471-4159.2007.04857.X

21 January 2018

Identifiers

DOI

1 reference

13 May 2018

1 reference

13 May 2018