(Q53301813)

13 May 2018

editorial

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title

Cancer caused by too much apoptosis--an intriguing contradiction? (English)

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13 May 2018

author

Thomas Kaufmann

series ordinal

2

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13 May 2018

author name string

Philipp J Jost

series ordinal

1

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13 May 2018

language of work or name

English

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publication date

1 April 2010

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13 May 2018

published in

Hepatology

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13 May 2018

volume

51

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issue

4

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page(s)

1110-1112

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13 May 2018

Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice

cites work

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Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes.

21 January 2018

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Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

21 January 2018

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Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.

21 January 2018

1 reference

21 January 2018

The Hallmarks of Cancer

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Caspases in cell survival, proliferation and differentiation.

21 January 2018

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The many roles of FAS receptor signaling in the immune system

21 January 2018

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Survivin, cancer networks and pathway-directed drug discovery.

21 January 2018

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Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 January 2018

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TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality.

21 January 2018

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Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

21 January 2018

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CD95, BIM and T cell homeostasis

21 January 2018

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/HEP.23514

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13 May 2018

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13 May 2018