(Q53305151)

13 May 2018

title

Intrachromosomal mitotic nonallelic homologous recombination is the major molecular mechanism underlying type-2 NF1 deletions. (English)

1 reference

13 May 2018

author

Nadia Chuzhanova

7

1 reference

13 May 2018

David N. Cooper

11

1 reference

13 May 2018

Hildegard Kehrer-Sawatzki

12

Hildegard Kehrer-Sawatzki

1 reference

13 May 2018

Victor-Felix Mautner

10

Victor-Felix Mautner

1 reference

13 May 2018

Josef Högel

6

Josef Högel

1 reference

13 May 2018

Tanja Mussotter

3

Tanja Mussotter

1 reference

13 May 2018

Lan Kluwe

9

Lan Kluwe

1 reference

13 May 2018

author name string

Angelika C Roehl

1

1 reference

13 May 2018

Julia Vogt

2

1 reference

13 May 2018

Antje N Zickler

4

1 reference

13 May 2018

Helene Spöti

5

1 reference

13 May 2018

Katharina Wimmer

8

1 reference

13 May 2018

publication date

1 October 2010

1 reference

13 May 2018

published in

Human Mutation

1 reference

13 May 2018

volume

31

1 reference

13 May 2018

page(s)

1163-1173

1 reference

13 May 2018

issue

10

1 reference

13 May 2018

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

cites work

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

Cloning and characterization of small circular DNA from Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

Translocation and gross deletion breakpoints in human inherited disease and cancer I: Nucleotide composition and recombination-associated motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Comparison of the duration of spermatogenesis between male rodents and humans

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mammalian meiotic recombination hot spots

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Microdeletions and microinsertions causing human genetic disease: common mechanisms of mutagenesis and the role of local DNA sequence complexity.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Nonrecurrent MECP2 duplications mediated by genomic architecture-driven DNA breaks and break-induced replication repair.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A positive but complex association between meiotic double-strand break hotspots and open chromatin in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Predicting DNA duplex stability from the base sequence

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Distinct histone modifications define initiation and repair of meiotic recombination in the mouse

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Double Holliday junctions are intermediates of DNA break repair.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Evolution in health and medicine Sackler colloquium: Genomic disorders: a window into human gene and genome evolution

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Gene conversion causing human inherited disease: evidence for involvement of non-B-DNA-forming sequences and recombination-promoting motifs in DNA breakage and repair

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

High-resolution patterns of meiotic recombination across the human major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Conservation of hotspots for recombination in low-copy repeats associated with the NF1 microdeletion.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

From meiosis to postmeiotic events: alignment and recognition of homologous chromosomes in meiosis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

NF1 microdeletion breakpoints are clustered at flanking repetitive sequences.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Genomic context of paralogous recombination hotspots mediating recurrent NF1 region microdeletion

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Homologous chromosome interactions in meiosis: diversity amidst conservation.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mechanisms for human genomic rearrangements

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

On the complexity measures of genetic sequences.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mitotic recombination map of 13cen-13q14 derived from an investigation of loss of heterozygosity in retinoblastomas

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A microhomology-mediated break-induced replication model for the origin of human copy number variation

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A mitotic recombination map proximal to the APC locus on chromosome 5q and assessment of influences on colorectal cancer risk

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

The rise and fall of a human recombination hot spot

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Where the crossovers are: recombination distributions in mammals.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

High frequency of mosaicism among patients with neurofibromatosis type 1 (NF1) with microdeletions caused by somatic recombination of the JJAZ1 gene

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Recombination proteins in yeast

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Sotos syndrome common deletion is mediated by directly oriented subunits within inverted Sos-REP low-copy repeats.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Nucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint library

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Processes of de novo duplication of human alpha-globin genes.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A DNA replication mechanism for generating nonrecurrent rearrangements associated with genomic disorders

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A chromosomal rearrangement hotspot can be identified from population genetic variation and is coincident with a hotspot for allelic recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Unequal meiotic crossover: a frequent cause of NF1 microdeletions.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Recombination hotspot in NF1 microdeletion patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Hotspots of homologous recombination in the human genome: not all homologous sequences are equal

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Genomic disorders ten years on.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Genomic disorders: molecular mechanisms for rearrangements and conveyed phenotypes

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Genomic analysis of cancer tissue reveals that somatic mutations commonly occur in a specific motif.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Cell biology: chromosome territories.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Duplication hotspots, rare genomic disorders, and common disease

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Condensins regulate meiotic DNA break distribution, thus crossover frequency, by controlling chromosome structure

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A fine-scale map of recombination rates and hotspots across the human genome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A common sequence motif associated with recombination hot spots and genome instability in humans

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Baseline expression profile of meiotic-specific genes in healthy fertile males.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mammalian recombination hot spots: properties, control and evolution.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Prdm9 controls activation of mammalian recombination hotspots

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mitotic recombination mediated by the JJAZF1 (KIAA0160) gene causing somatic mosaicism and a new type of constitutional NF1 microdeletion in two children of a mosaic female with only few manifestations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Human meiotic recombination products revealed by sequencing a hotspot for homologous strand exchange in multiple HNPP deletion patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Meiotic chromosomes: it takes two to tango

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Extended runs of homozygosity at 17q11.2: an association with type-2NF1deletions?

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Genome destabilization by homologous recombination in the germ line

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mitotic recombination effects homozygosity for NF1 germline mutations in neurofibromas

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Differential gene expression of mammalian SPO11/TOP6A homologs during meiosis.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Implications of human genome architecture for rearrangement-based disorders: the genomic basis of disease

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Uncommon deletions of the Smith-Magenis syndrome region can be recurrent when alternate low-copy repeats act as homologous recombination substrates

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Structural variation in the human genome and its role in disease

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Type 2 NF1 deletions are highly unusual by virtue of the absence of nonallelic homologous recombination hotspots and an apparent preference for female mitotic recombination

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Copy number variations in the NF1 gene region are infrequent and do not predispose to recurrent type-1 deletions

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Mechanisms of loss of heterozygosity in neurofibromatosis type 1-associated plexiform neurofibromas.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Interstitial uniparental isodisomy at clustered breakpoint intervals is a frequent mechanism of NF1 inactivation in myeloid malignancies

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

From meiosis to postmeiotic events: homologous recombination is obligatory but flexible

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Parental and chromosomal origins of microdeletion and duplication syndromes involving 7q11.23, 15q11-q13 and 22q11

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Analysis of meiotic recombination in 22q11.2, a region that frequently undergoes deletions and duplications

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Germline rates of de novo meiotic deletions and duplications causing several genomic disorders

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Gross deletions of the neurofibromatosis type 1 (NF1) gene are predominantly of maternal origin and commonly associated with a learning disability, dysmorphic features and developmental delay.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

The spectrum of somatic and germline NF1 mutations in NF1 patients with spinal neurofibromas.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Identification of a 3.0-kb major recombination hotspot in patients with Sotos syndrome who carry a common 1.9-Mb microdeletion

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Rare pathogenic microdeletions and tandem duplications are microhomology-mediated and stimulated by local genomic architecture

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Non-B DNA conformations, mutagenesis and disease

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Alu repeats increase local recombination rates

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Anatomy of mouse recombination hot spots

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Meiotic cells monitor the status of the interhomolog recombination complex

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

A probabilistic model for the arrangement of a subset of human chromosome territories in WI38 human fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Complex human chromosomal and genomic rearrangements

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Copy number variation in human health, disease, and evolution

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Identification of uncommon recurrent Potocki-Lupski syndrome-associated duplications and the distribution of rearrangement types and mechanisms in PTLS

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.21340

7 January 2021

Identifiers

DOI

10.1002/HUMU.21340

1 reference

13 May 2018

PubMed ID

20725927

1 reference

13 May 2018