(Q53337645)

13 May 2018

title

Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells. (English)

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13 May 2018

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5

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Oliver Renner

object named as

O Renner

2

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Wolfgang Link

object named as

W Link

8

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Amancio Carnero

object named as

A Carnero

7

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author name string

F Zanella

1

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13 May 2018

B García

3

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S Callejas

4

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S Peregrina

6

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13 May 2018

language of work or name

English

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publication date

8 March 2010

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13 May 2018

published in

Oncogene

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volume

29

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issue

20

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13 May 2018

page(s)

2973-2982

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/onc.2010.58

exact match

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cites work

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

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3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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https://api.crossref.org/works/10.1038%2FONC.2010.58

Unravelling the tumor-suppressive functions of FOXO proteins

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Resist or die: FOXO transcription factors determine the cellular response to chemotherapy.

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A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila

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The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

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Tribbles: novel regulators of cell function; evolutionary aspects

21 January 2018

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Tribbles: a family of kinase-like proteins with potent signalling regulatory function.

21 January 2018

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qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

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https://api.crossref.org/works/10.1038%2FONC.2010.58

Involvement of FKHRL1 in melanoma cell survival and death.

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IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

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Dynamic FoxO transcription factors

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Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells

21 January 2018

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Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia

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Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis

21 January 2018

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Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.

21 January 2018

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The emerging roles of forkhead box (Fox) proteins in cancer

21 January 2018

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FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

21 January 2018

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A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling

21 January 2018

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Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

21 January 2018

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Apoptosis and melanoma chemoresistance

21 January 2018

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Constitutively active FOXO4 inhibits Akt activity, regulates p27 Kip1 stability, and suppresses HER2-mediated tumorigenicity

21 January 2018

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An HTS approach to screen for antagonists of the nuclear export machinery using high content cell-based assays

21 January 2018

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Chemical genetic analysis of FOXO nuclear-cytoplasmic shuttling by using image-based cell screening

21 January 2018

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Using multiplexed regulation of luciferase activity and GFP translocation to screen for FOXO modulators

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/ONC.2010.58

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13 May 2018

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13 May 2018