(Q53346452)

English

Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.

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scholarly article

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis. (English)

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

apoptotic process

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2

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

3

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

author name string

Kwang Seok Ahn

1

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

Anil K Jaiswal

4

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

Bharat B Aggarwal

5

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

language of work or name

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publication date

8 May 2006

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

Journal of Biological Chemistry

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

281

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13 May 2018

http://europepmc.org/abstract/MED/16682409

19798-19808

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

29

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

Antioxidant response element

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NQO1 stabilizes p53 through a distinct pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NAD(P)H: quinone oxidoreductase polymorphism and lung cancer in Taiwan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Signalling pathways of the TNF superfamily: a double-edged sword

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Reactive oxygen intermediates in TNF signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

The human dioxin-inducible NAD(P)H: quinone oxidoreductase cDNA-encoded protein expressed in COS-1 cells is identical to diaphorase 4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Assay for redox-sensitive transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Nuclear transcription factor-kappaB as a target for cancer drug development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaB(alpha): correlation with induction of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Transcription factor NF-kappaB: a sensor for smoke and stress signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Regulation of proliferation, survival and apoptosis by members of the TNF superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Nuclear factor-kappaB: the enemy within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

IkappaB kinase: beginning, not the end

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Dicoumarol alters cellular redox state and inhibits nuclear factor kappa B to enhance arsenic trioxide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Quinone reductase inhibitors block SAPK/JNK and NFkappaB pathways and potentiate apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

The essential role of MEKK3 in TNF-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Human NAD(P)H:quinone oxidoreductase inhibition by flavonoids in living cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Differential IκB Kinase Activation and IκBα Degradation by Interleukin-1β and Tumor Necrosis Factor-α in Human U937 Monocytic Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M601162200

21 January 2018

Identifiers

10.1074/JBC.M601162200

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/16682409

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