(Q53356205)

13 May 2018

title

Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis. (English)

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13 May 2018

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Aaron Pollett

5

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author name string

Michael A Ko

1

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13 May 2018

Carla O Rosario

2

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13 May 2018

John W Hudson

3

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13 May 2018

Sarang Kulkarni

4

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13 May 2018

James W Dennis

6

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13 May 2018

Carol J Swallow

7

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13 May 2018

language of work or name

English

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publication date

17 July 2005

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13 May 2018

published in

Nature Genetics

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13 May 2018

volume

37

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13 May 2018

issue

8

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13 May 2018

page(s)

883-888

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/ng1605

exact match

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cites work

Constitutive expression of murine Sak-a suppresses cell growth and induces multinucleation

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Late mitotic failure in mice lacking Sak, a polo-like kinase.

21 January 2018

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7 January 2021

Cell cycle checkpoints: preventing an identity crisis

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7 January 2021

Pathways of apoptotic and non-apoptotic death in tumour cells

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7 January 2021

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

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7 January 2021

p27(Kip1): regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer.

1 reference

7 January 2021

Slippage of mitotic arrest and enhanced tumor development in mice with BubR1 haploinsufficiency

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7 January 2021

Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

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7 January 2021

ARF mutation accelerates pituitary tumor development in Rb+/- mice.

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7 January 2021

Haploinsufficiency of p18(INK4c) sensitizes mice to carcinogen-induced tumorigenesis

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7 January 2021

Principles of tumor suppression

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7 January 2021

Polo-like kinases and the orchestration of cell division

1 reference

7 January 2021

Polar expeditions--provisioning the centrosome for mitosis.

1 reference

7 January 2021

Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells

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7 January 2021

Multiple genetic alterations, 4q28, a new suppressor region, and potential gender differences in human hepatocellular carcinoma

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7 January 2021

A plus-end raft to control microtubule dynamics and function

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7 January 2021

Molecular and cellular features of hepatic regeneration

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7 January 2021

Akt1/PKB upregulation leads to vascular smooth muscle cell hypertrophy and polyploidization.

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7 January 2021

Loss of p53 and centrosome hyperamplification.

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7 January 2021

The promoter region of the human BUBR1 gene and its expression analysis in lung cancer

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7 January 2021

Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability

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7 January 2021

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

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7 January 2021

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

1 reference

7 January 2021

Sak/Plk4 and mitotic fidelity

1 reference

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

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7 January 2021

Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis

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7 January 2021

The cat and mouse games that genes, viruses, and cells play

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7 January 2021

Specific association between alcohol intake, high grade of differentiation and 4q34-q35 deletions in hepatocellular carcinomas identified by high resolution allelotyping

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7 January 2021

Chromosomal allelic imbalance evolving from liver cirrhosis to hepatocellular carcinoma

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7 January 2021

Identifiers

DOI

10.1038/NG1605

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13 May 2018

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13 May 2018