(Q53422658)

14 May 2018

title

Caspase signalling controls microglia activation and neurotoxicity. (English)

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14 May 2018

Albert Garcia-Quintanilla

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1 reference

Albert Garcia-Quintanilla

6

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José L. Venero

Jose L Venero

10

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Elisabet Englund

Elisabet Englund

9

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Sam Brundin

8

Patrik Brundin

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14 May 2018

Miguel A Burguillos

1

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14 May 2018

Tomas Deierborg

2

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14 May 2018

Edel Kavanagh

3

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14 May 2018

Annette Persson

4

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14 May 2018

Nabil Hajji

5

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14 May 2018

Josefina Cano

7

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14 May 2018

Bertrand Joseph

11

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14 May 2018

language of work or name

English

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publication date

9 March 2011

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14 May 2018

published in

Nature

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14 May 2018

volume

472

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14 May 2018

issue

7343

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14 May 2018

page(s)

319-324

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14 May 2018

https://scigraph.springernature.com/pub.10.1038/nature09788

exact match

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cites work

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Serial killers: ordering caspase activation events in apoptosis

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Autocrine activation of microglia by tumor necrosis factor-alpha

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Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide

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Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation

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An immortalized cell line expresses properties of activated microglial cells

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Caspases and neuroprotection.

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12 December 2020

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.

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Role of cytokines in neurological disorders

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IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways

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12 December 2020

Activated microglia mediate neuronal cell injury via a nitric oxide mechanism

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12 December 2020

NF-kappa B activation in tumor necrosis factor alpha-stimulated neutrophils is mediated by protein kinase Cdelta. Correlation to nuclear Ikappa Balpha

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12 December 2020

Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease

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Inflammation as therapeutic objective in stroke

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Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induced Parkinson's disease mice model

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The duality of the inflammatory response to traumatic brain injury

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Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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12 December 2020

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker

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Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment

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12 December 2020

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

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12 December 2020

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

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12 December 2020

Active caspase-1 is a regulator of unconventional protein secretion

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12 December 2020

The apoptotic signaling pathway activated by Toll-like receptor-2

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12 December 2020

Protein kinase C delta is essential for etoposide-induced apoptosis in salivary gland acinar cells

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12 December 2020

Lipopolysaccharide intranigral injection induces inflammatory reaction and damage in nigrostriatal dopaminergic system

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12 December 2020

Caspases: the proteases of the apoptotic pathway

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12 December 2020

Apoptosis and caspases in neurodegenerative diseases

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12 December 2020

Interferon gamma receptor deficient mice are resistant to endotoxic shock

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12 December 2020

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

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12 December 2020

A nanomedicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection.

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12 December 2020

Characterization of ameboid microglia isolated from developing mammalian brain.

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12 December 2020

Microglia as mediators of inflammatory and degenerative diseases

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12 December 2020

Blood-brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons

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12 December 2020

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

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12 December 2020

Inflammation in central nervous system injury

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12 December 2020

Neuroprotection by a caspase inhibitor in acute bacterial meningitis

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12 December 2020

Signaling to NF-kappaB by Toll-like receptors

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12 December 2020

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

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12 December 2020

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

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12 December 2020

Caspases: the executioners of apoptosis

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12 December 2020

Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling

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12 December 2020

Identifiers

DOI

10.1038/NATURE09788

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14 May 2018

Dimensions Publication ID

1000901815

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1 reference

14 May 2018