(Q53438253)

English

Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties.

scientific article published on 14 February 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties. (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

1 reference

ChEBI release 2020-05-28

Herman O. Sintim

2

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

author name string

Jingxin Wang

1

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

language of work or name

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publication date

14 February 2011

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

Chemistry—A European Journal

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

17

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

12

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

3352-3357

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Total synthesis of (-)-platensimycin, a novel antibacterial agent

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

A carbonyl ylide cycloaddition approach to platensimycin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Enantioselective route to platensimycin: an intramolecular Robinson annulation approach

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

A concise ring-expansion route to the compact core of platensimycin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Stereoelectronic effect for the selectivity in C-H insertion of alkylidene carbenes and its application to the synthesis of platensimycin.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Formal synthesis of (+/-)-platensimycin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

A symmetry-based concise formal synthesis of platencin, a novel lead against "superbugs".

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

An expedient asymmetric synthesis of platencin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

A nine-step total synthesis of (-)-platencin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Formal total synthesis of platencin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

High-pressure entry into platencin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin: more potent analogs of platensimycin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Isoplatensimycin: Synthesis and biological evaluation.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Total synthesis and antibacterial properties of carbaplatensimycin.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Synthesis and biological evaluation of platensimycin analogs

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Efforts towards the identification of simpler platensimycin analogues--the total synthesis of oxazinidinyl platensimycin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Synthesis and antibacterial properties of (-)-nor-platencin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Discovery and syntheses of "superbug challengers"-platensimycin and platencin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Inhibiting bacterial fatty acid synthesis

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

AcrB multidrug efflux pump of Escherichia coli: composite substrate-binding cavity of exceptional flexibility generates its extremely wide substrate specificity

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Biosynthesis of Erythromycin and Rapamycin.

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Function-oriented synthesis, step economy, and drug design

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Function-oriented synthesis of simplified caprazamycins: discovery of oxazolidine-containing uridine derivatives as antibacterial agents against drug-resistant bacteria

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Function-oriented synthesis: biological evaluation of laulimalide analogues derived from a last step cross metathesis diversification strategy

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Function-oriented synthesis applied to the anti-botulinum natural product toosendanin

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Determination of selectivity and efficacy of fatty acid synthesis inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

The mechanism of isoniazid killing: clarity through the scope of genetics

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Antibacterial targets in fatty acid biosynthesis

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201002410

21 January 2018

Identifiers

10.1002/CHEM.201002410

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 May 2018

http://europepmc.org/abstract/MED/21322068

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