(Q53526983)

English

Inhibition of NF-kappaB activation by the histone deacetylase inhibitor 4-Me2N-BAVAH induces an early G1 cell cycle arrest in primary hepatocytes.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17877607

Inhibition of NF-kappaB activation by the histone deacetylase inhibitor 4-Me2N-BAVAH induces an early G1 cell cycle arrest in primary hepatocytes. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17877607

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2

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

5

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Europe PubMed Central

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14 May 2020

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

author name string

P Papeleu

1

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14 May 2020

G Elaut

3

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14 May 2020

T Henkens

4

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14 May 2020

G Laus

6

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14 May 2020

D Tourwé

7

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14 May 2020

V Rogiers

9

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14 May 2020

T Vanhaecke

10

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14 May 2020

publication date

1 October 2007

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17877607

Cell Proliferation

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PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

40

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14 May 2020

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

640-655

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression

1 reference

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21 January 2018

Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells.

1 reference

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21 January 2018

The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

NF-kappaB and cell-cycle regulation: the cyclin connection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Histone acetylases and deacetylases in cell proliferation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Histone deacetylase inhibitors in programmed cell death and cancer therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Histone deacetylases and cancer: causes and therapies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF-kappa B through the Akt pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

The NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

A review of depsipeptide and other histone deacetylase inhibitors in clinical trials

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Trichostatin A-like hydroxamate histone deacetylase inhibitors as therapeutic agents: toxicological point of view

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Alteration of nucleosome structure as a mechanism of transcriptional regulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Adenoviral gene transfer of ABIN-1 protects mice from TNF/galactosamine-induced acute liver failure and lethality

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Histone deacetylase as a new target for cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Amide Analogues of Trichostatin A as Inhibitors of Histone Deacetylase and Inducers of Terminal Cell Differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2184.2007.00466.X

21 January 2018

Adenoviral gene transfer of the NF-kappa B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat hepatocyte suspensions as a suitable in vitro model for studying the biotransformation of histone deacetylase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Additive effect of p53, p21 and Rb deletion in triple knockout primary hepatocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major phase I biotransformation pathways of Trichostatin a in rat hepatocytes and in rat and human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of histone deacetylase inhibitors in tumor and normal cells-what is the toxicological relevance?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of rat hepatocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proliferation of epidermal growth factor-stimulated hepatocytes in a hormonally defined serum-free medium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional profiling of liver regeneration: new approaches to an old trick!

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different accessibilities in chromatin to histone acetylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged Jun N-terminal kinase (JNK) activation and the upregulation of p53 and p21(WAF1/CIP1) preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient expression of cyclin D1 is sufficient to promote hepatocyte replication and liver growth in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trichostatin a enhances gap junctional intercellular communication in primary cultures of adult rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A20, an inhibitor of cell death, self-associates by its zinc finger domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and apoptosis related proteins in chronic viral liver disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A metabolic screening study of trichostatin A (TSA) and TSA-like histone deacetylase inhibitors in rat and human primary hepatocyte cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin D1 promotes mitogen-independent cell cycle progression in hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin kinase inhibitor p21 potentiates bile acid-induced apoptosis in hepatocytes that is dependent on p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour necrosis factor alpha decreases glucose-6-phosphatase gene expression by activation of nuclear factor kappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trichostatin A, a critical factor in maintaining the functional differentiation of primary cultured rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17877607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2184.2007.00466.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496027&resulttype=core&format=json

14 May 2020

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