(Q53547073)

15 May 2018

title

Transplanted hepatocytes over-expressing FoxM1B efficiently repopulate chronically injured mouse liver independent of donor age. (English)

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15 May 2018

6

Dina Kremsdorf

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15 May 2018

author name string

Nicolas Brezillon

1

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15 May 2018

Martine Lambert-Blot

2

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15 May 2018

Serban Morosan

3

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15 May 2018

Dominique Couton

4

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15 May 2018

Claudia Mitchell

5

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Robert H Costa

7

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15 May 2018

Helene Gilgenkrantz

8

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15 May 2018

Jacques-Emmanuel Guidotti

9

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15 May 2018

publication date

12 June 2007

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15 May 2018

published in

Molecular Therapy

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15 May 2018

volume

15

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15 May 2018

issue

9

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15 May 2018

page(s)

1710-1715

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15 May 2018

Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation

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FoxM1 is required for execution of the mitotic programme and chromosome stability

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Forkhead box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators

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The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration

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The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis

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Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor Trident

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Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase

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Increased hepatic Forkhead Box M1B (FoxM1B) levels in old-aged mice stimulated liver regeneration through diminished p27Kip1 protein levels and increased Cdc25B expression

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Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome

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Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine

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Loss of p27(Kip1) enhances the transplantation efficiency of hepatocytes transferred into diseased livers

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p27Kip1 inactivation provides a proliferative advantage to transplanted hepatocytes in DPPIV/Rag2 double knockout mice after repeated host liver injury.

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7 January 2021

Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions

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The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Heparin-binding epidermal growth factor-like growth factor links hepatocyte priming with cell cycle progression during liver regeneration

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300232

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15 May 2018

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15 May 2018