(Q53561930)

15 May 2018

title

p53 and Delta Np63 alpha differentially bind and regulate target genes involved in cell cycle arrest, DNA repair and apoptosis. (English)

1 reference

15 May 2018

author name string

Schavolt KL

series ordinal

1

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15 May 2018

Pietenpol JA

series ordinal

2

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15 May 2018

language of work or name

English

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publication date

2 April 2007

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15 May 2018

published in

Oncogene

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15 May 2018

volume

26

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15 May 2018

issue

42

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15 May 2018

page(s)

6125-6132

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15 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210441

exact match

0 references

cites work

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

IGFBP-3 is a direct target of transcriptional regulation by DeltaNp63alpha in squamous epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Regulation of the cyclin-dependent kinase inhibitor p57Kip2 expression by p63.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Post-translational modification of p53 in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

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p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

The common and distinct target genes of the p53 family transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Perp is a p63-regulated gene essential for epithelial integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

p63 is an essential proapoptotic protein during neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Promoter-specific p53-dependent histone acetylation following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Kinetics of p53 binding to promoter sites in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice.

21 January 2018

1 reference

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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

21 January 2018

1 reference

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Comparative binding of p53 to its promoter and DNA recognition elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

p63: Molecular complexity in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

A functional p53-responsive intronic promoter is contained within the humanmdm2gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

Phosphorylation of p53 serine 15 increases interaction with CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

inferred from DOI database lookup

7 January 2021

based on heuristic

Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210441

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210441

1 reference

15 May 2018

1 reference

15 May 2018