(Q53568387)

15 May 2018

title

Focal adhesion kinase is required for CXCL12-induced chemotactic and pro-adhesive responses in hematopoietic precursor cells. (English)

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15 May 2018

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5

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15 May 2018

author name string

Glodek AM

1

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15 May 2018

Le Y

2

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15 May 2018

Dykxhoorn DM

3

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15 May 2018

Park SY

4

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15 May 2018

Mulligan R

6

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15 May 2018

Lieberman J

7

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15 May 2018

Beggs HE

8

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15 May 2018

Honczarenko M

9

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15 May 2018

Silberstein LE

10

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15 May 2018

publication date

14 June 2007

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15 May 2018

published in

Leukemia

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15 May 2018

volume

21

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15 May 2018

issue

8

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15 May 2018

page(s)

1723-1732

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15 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404769

exact match

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cites work

CXC chemokine ligand 12-induced focal adhesion kinase activation and segregation into membrane domains is modulated by regulator of G protein signaling 1 in pro-B cells

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The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration.

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The stem-cell niche as an entity of action

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7 January 2021

Cross-talk between alpha(4)beta(1)/alpha(5)beta(1) and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways

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Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

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Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

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7 January 2021

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

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7 January 2021

The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment

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The role of G-protein signaling in hematopoietic stem/progenitor cell mobilization.

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Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing.

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Effects of the chemokine stromal cell-derived factor-1 on the migration and localization of precursor-B acute lymphoblastic leukemia cells within bone marrow stromal layers.

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The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow.

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Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling

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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

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Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist

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Current mechanistic scenarios in hematopoietic stem/progenitor cell mobilization

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Sustained activation of cell adhesion is a differentially regulated process in B lymphopoiesis

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Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-dependent adhesion to fibronectin and VCAM-1 on bone marrow hematopoietic progenitor cells

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Role of CXCR4 chemokine receptor blockade using AMD3100 for mobilization of autologous hematopoietic progenitor cells

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Focal adhesion kinase: in command and control of cell motility

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7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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7 January 2021

Lentivirus-delivered stable gene silencing by RNAi in primary cells

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Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer

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Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation.

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7 January 2021

FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies

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7 January 2021

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

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7 January 2021

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

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7 January 2021

Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells

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7 January 2021

Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12

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7 January 2021

Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow

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7 January 2021

Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1

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7 January 2021

Intracellular signalling controlling integrin activation in lymphocytes

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7 January 2021

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

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7 January 2021

Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL.

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7 January 2021

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

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7 January 2021

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

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7 January 2021

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

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7 January 2021

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

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7 January 2021

Bidirectional signaling between the cytoskeleton and integrins

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7 January 2021

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

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7 January 2021

Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosis

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7 January 2021

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

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7 January 2021

Role of the cytoskeleton during leukocyte responses

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7 January 2021

p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

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7 January 2021

Rac2-deficient hematopoietic stem cells show defective interaction with the hematopoietic microenvironment and long-term engraftment failure.

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404769

1 reference

15 May 2018

1 reference

15 May 2018