(Q53589410)

16 May 2018

title

Sildenafil-mediated acute cardioprotection is independent of the NO/cGMP pathway. (English)

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16 May 2018

author

John W. Elrod

series ordinal

1

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16 May 2018

author name string

James J M Greer

series ordinal

2

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16 May 2018

David J Lefer

series ordinal

3

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16 May 2018

publication date

1 September 2006

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16 May 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

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16 May 2018

volume

292

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16 May 2018

issue

1

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16 May 2018

page(s)

H342-7

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16 May 2018

Mechanism of cGMP-mediated protection in a cellular model of myocardial reperfusion injury

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Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism

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Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits

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Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling.

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Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity

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Sildenafil citrate increases myocardial cGMP content in rat heart, decreases its hypertrophic response to isoproterenol and decreases myocardial leak of creatine kinase and troponin T

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Pretreatment with simvastatin attenuates myocardial dysfunction after ischemia and chronic reperfusion

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21 January 2018

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cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism

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Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy

21 January 2018

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10.1152/AJPHEART.00306.2006

21 January 2018

Identifiers

DOI

1 reference

16 May 2018

1 reference

16 May 2018