(Q53615275)

16 May 2018

title

Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana. (English)

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16 May 2018

cysteine peptidase B (CPB)

main subject

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GeneDB

cysteine peptidase A (CPA)

5 February 2019

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5 February 2019

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Leishmania mexicana

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1

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16 May 2018

Jeremy C. Mottram

series ordinal

3

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16 May 2018

Laurence Tetley

series ordinal

2

object named as

Laurence Tetley

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16 May 2018

author name string

Graham H Coombs

series ordinal

4

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16 May 2018

language of work or name

English

0 references

publication date

27 June 2006

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16 May 2018

published in

Molecular Microbiology

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16 May 2018

volume

61

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16 May 2018

page(s)

655-674

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16 May 2018

issue

3

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16 May 2018

Cytoskeletal elements are required for the formation and maturation of autophagic vacuoles

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1 reference

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Leishmania mexicana: induction of metacyclogenesis by cultivation of promastigotes at acidic pH.

21 January 2018

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Induction of autophagic cell death in Leishmania donovani by antimicrobial peptides

21 January 2018

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Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major.

21 January 2018

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Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships

21 January 2018

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Autophagy and intracellular surveillance: Modulating MHC class II antigen presentation with stress

21 January 2018

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Autophagy promotes MHC class II presentation of peptides from intracellular source proteins

21 January 2018

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Sphingolipid-free Leishmania are defective in membrane trafficking, differentiation and infectivity.

21 January 2018

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Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae

21 January 2018

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Studies on the mechanisms of autophagy: maturation of the autophagic vacuole

21 January 2018

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Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions.

21 January 2018

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Analysis of the roles of cysteine proteinases of Leishmania mexicana in the host-parasite interaction

21 January 2018

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Secretory and endocytic pathways converge in a dynamic endosomal system in a primitive protozoan

21 January 2018

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Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene.

21 January 2018

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Autophagy and related processes in trypanosomatids: insights from genomic and bioinformatic analyses

21 January 2018

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A ubiquitin-like system mediates protein lipidation

21 January 2018

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In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy

21 January 2018

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Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion

21 January 2018

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The genome of the kinetoplastid parasite, Leishmania major

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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A modified colorimetric assay of macrophage activation for intracellular cytotoxicity against Leishmania parasites

21 January 2018

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Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation

21 January 2018

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A Unified Nomenclature for Yeast Autophagy-Related Genes

21 January 2018

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Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

21 January 2018

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Autophagy gene disruption reveals a non-vacuolar cell death pathway in Dictyostelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation

21 January 2018

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Development by self-digestion: molecular mechanisms and biological functions of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

The autophagic and endocytic pathways converge at the nascent autophagic vacuoles

21 January 2018

1 reference

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Leishmania tropica: cysteine proteases are essential for growth and pathogenicity

21 January 2018

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Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

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Methods for monitoring autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

A protein conjugation system essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Cysteine peptidases as virulence factors of Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Regulated degradation of an endoplasmic reticulum membrane protein in a tubular lysosome in Leishmania mexicana

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Proteomic analysis of Leishmania mexicana differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Two ubiquitin-like conjugation systems essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Autophagosomes: biogenesis from scratch?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Improvements in transfection efficiency and tests of RNA interference (RNAi) approaches in the protozoan parasite Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Starvation-induced expression of autophagy-related genes in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Metacyclogenesis in Leishmania promastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Autophagy and other vacuolar protein degradation mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Cysteine protease inhibitors as chemotherapy: lessons from a parasite target

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Characterization of a multi-copy gene for a major stage-specific cysteine proteinase of Leishmania mexicana

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

3-methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

LC3 conjugation system in mammalian autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

How Well is Enzyme Function Conserved as a Function of Pairwise Sequence Identity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Developmental changes in lysosome morphology and function Leishmania parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Autophagy: a regulated bulk degradation process inside cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Sphingolipids are essential for differentiation but not growth in Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

Implications of a genomic search for autophagy-related genes in trypanosomatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2958.2006.05274.X

10.1111/J.1365-2958.2006.05274.X

21 January 2018

Identifiers

DOI

1 reference

16 May 2018

PubMed ID

16803590

1 reference

16 May 2018