(Q53663330)

17 May 2018

title

Characterization of the 19q12 amplification including CCNE1 and URI in different epithelial ovarian cancer subtypes. (English)

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17 May 2018

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9

Holger Moch

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17 May 2018

author name string

Aurelia Noske

1

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17 May 2018

Leigh A Henricksen

2

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17 May 2018

Bonnie LaFleur

3

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Anne-Katrin Zimmermann

4

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Alisa Tubbs

5

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Shalini Singh

6

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17 May 2018

Martina Storz

7

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17 May 2018

Daniel Fink

8

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17 May 2018

publication date

16 December 2014

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17 May 2018

Experimental and Molecular Pathology

published in

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17 May 2018

volume

98

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17 May 2018

issue

1

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17 May 2018

page(s)

47-54

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17 May 2018

Cyclin E deregulation alters the biologic properties of ovarian cancer cells.

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Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer

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Synthetic lethality between CCNE1 amplification and loss of BRCA1.

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Resistance to CDK2 inhibitors is associated with selection of polyploid cells in CCNE1-amplified ovarian cancer

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Limited prognostic value of tissue protein expression levels of cyclin E in Danish ovarian cancer patients: from the Danish 'MALOVA' ovarian cancer study.

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Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube-derived high-grade serous ovarian cancers.

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Frequent CCNE1 amplification in endometrial intraepithelial carcinoma and uterine serous carcinoma

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Cell cycle kinases as therapeutic targets for cancer

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Comprehensive analysis of 19q12 amplicon in human gastric cancers.

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Analysis of gene amplification and prognostic markers in ovarian cancer using comparative genomic hybridization for microarrays and immunohistochemical analysis for tissue microarrays

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Functional characterization of the 19q12 amplicon in grade III breast cancers

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Cyclin E1 (CCNE1) as independent positive prognostic factor in advanced stage serous ovarian cancer patients - a study of the OVCAD consortium

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TP53 mutations are common in all subtypes of epithelial ovarian cancer and occur concomitantly with KRAS mutations in the mucinous type

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Cyclin E overexpression and amplification in human tumours

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An integrated view of cyclin E function and regulation

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URI is an oncogene amplified in ovarian cancer cells and is required for their survival

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Identifiers

DOI

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17 May 2018

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17 May 2018