(Q53675615)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

author name string

Nolan R Filipenko

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Sarah Attwell

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Calvin Roskelley

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

language of work or name

English

0 references

publication date

1 September 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

page(s)

5837-5849

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

issue

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15897874%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208737

11 January 2020

exact match

0 references

cites work

WIP participates in actin reorganization and ruffle formation induced by PDGF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

The integrin-linked kinase (ILK) suppresses anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

The integrin-actin connection, an eternal love affair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-mediated signals regulated by members of the rho family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Cell-substrate interactions and signaling through ILK

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin cytoplasmic interactions and bidirectional transmembrane signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin signaling to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Rho GTPases in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked kinase regulates chondrocyte shape and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Role of the PI3K regulatory subunit in the control of actin organization and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Genetic deletion of the Pten tumor suppressor gene promotes cell motility by activation of Rac1 and Cdc42 GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Tumor progression: Small GTPases and loss of cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Cell migration: Rho GTPases lead the way

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Cell migration: integrating signals from front to back

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

AlphaPIX associates with calpain 4, the small subunit of calpain, and has a dual role in integrin-mediated cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Regulation of tumor angiogenesis by integrin-linked kinase (ILK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Solution structure of the focal adhesion adaptor PINCH LIM1 domain and characterization of its interaction with the integrin-linked kinase ankyrin repeat domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyrene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

inferred from DOI database lookup

7 January 2021

based on heuristic

Role of integrin-linked kinase in nerve growth factor-stimulated neurite outgrowth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737

inferred from DOI database lookup

7 January 2021

based on heuristic

A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208737