(Q53697056)

English

The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.

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22 March 2020

The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis (English)

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22 March 2020

Mycobacterium tuberculosis

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7

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22 March 2020

Katharina Weinhäupl

1

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22 March 2020

5

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22 March 2020

8

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22 March 2020

3

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Uli Kazmaier

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22 March 2020

author name string

Martha Brennich

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22 March 2020

Joel Lelievre

4

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22 March 2020

Alfred Goldberg

6

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22 March 2020

language of work or name

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publication date

9 April 2018

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22 March 2020

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15

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Journal of Biological Chemistry

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22 March 2020

293

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22 March 2020

22

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22 March 2020

8379-8393

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22 March 2020

Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control

1 reference

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7 September 2018

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

1 reference

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7 September 2018

Mutation analysis of the interactions between Mycobacterium tuberculosis caseinolytic protease C1 (ClpC1) and ecumicin.

1 reference

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7 September 2018

Mutation in clpC1 encoding an ATP-dependent ATPase involved in protein degradation is associated with pyrazinamide resistance in Mycobacterium tuberculosis

1 reference

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7 September 2018

A molecular mechanism of chaperone-client recognition.

1 reference

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7 September 2018

Online Size-exclusion and Ion-exchange Chromatography on a SAXS Beamline.

1 reference

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7 September 2018

Probing Conformational Exchange Dynamics in a Short-Lived Protein Folding Intermediate by Real-Time Relaxation-Dispersion NMR.

1 reference

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7 September 2018

Missense Mutations in the Unfoldase ClpC1 of the Caseinolytic Protease Complex Are Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis

1 reference

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7 September 2018

A Dynamic molecular basis for malfunction in disease mutants of p97/VCP.

1 reference

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7 September 2018

Arginine phosphorylation marks proteins for degradation by a Clp protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Modelling proteins' hidden conformations to predict antibiotic resistance

1 reference

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DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

1 reference

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7 September 2018

Total Synthesis of Cyclomarin A, a Marine Cycloheptapeptide with Anti-Tuberculosis and Anti-Malaria Activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Mechanisms of Pyrazinamide Action and Resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

The fast azimuthal integration Python library: pyFAI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Structural Basis of Mycobacterial Inhibition by Cyclomarin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Upgraded ESRF BM29 beamline for SAXS on macromolecules in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Advances in the development of new tuberculosis drugs and treatment regimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Protein-associated cation clusters in aqueous arginine solutions and their effects on protein stability and size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

The active ClpP protease from M. tuberculosis is a complex composed of a heptameric ClpP1 and a ClpP2 ring.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Structure and mechanism of the hexameric MecA-ClpC molecular machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Sequence-specific random coil chemical shifts of intrinsically disordered proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

An introduction to NMR-based approaches for measuring protein dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Interaction of arginine with proteins and the mechanism by which it inhibits aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Mycobacterium tuberculosis ClpC1: characterization and role of the N-terminal domain in its function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

The tyrosine kinase McsB is a regulated adaptor protein for ClpCP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

Adaptor protein controlled oligomerization activates the AAA+ protein ClpC

1 reference

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7 September 2018

Cyanobacterial ClpC/HSP100 protein displays intrinsic chaperone activity.

1 reference

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Intrinsic dynamics of an enzyme underlies catalysis

1 reference

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7 September 2018

Is arginine a protein-denaturant?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5986217

7 September 2018

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1 reference

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7 September 2018

Characterization of the N-terminal repeat domain of Escherichia coli ClpA-A class I Clp/HSP100 ATPase

1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/29632076

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/29632076

12 December 2020

based on heuristic

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Total synthesis of desoxycyclomarin C and the cyclomarazines A and B

1 reference

https://pubmed.ncbi.nlm.nih.gov/29632076

12 December 2020

based on heuristic

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Identifiers

10.1074/JBC.RA118.002251

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29632076%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

Europe PubMed Central

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22 March 2020

1 reference

Europe PubMed Central

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22 March 2020

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