(Q53798961)

English

Asymmetric dimethylarginine (ADMA) elevation and arginase up-regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbidly obese humans.

scientific article published on 4 March 2016

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scholarly article

1 reference

Europe PubMed Central

19 May 2018

http://europepmc.org/abstract/MED/26840628

Asymmetric dimethylarginine (ADMA) elevation and arginase up-regulation contribute to endothelial dysfunction related to insulin resistance in rats and morbidly obese humans. (English)

1 reference

Europe PubMed Central

19 May 2018

http://europepmc.org/abstract/MED/26840628

0 references

insulin resistance

1 reference

based on heuristic

inferred from title

Leocadio Rodríguez-Mañas

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Mariam El Assar

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Javier Angulo

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Marta Santos-Ruiz

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Juan Carlos Ruiz de Adana

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

María Luz Pindado

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Alberto Sánchez-Ferrer

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Alberto Hernández

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

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publication date

4 March 2016

1 reference

Europe PubMed Central

19 May 2018

http://europepmc.org/abstract/MED/26840628

Journal of Physiology

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

594

1 reference

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12 June 2020

11

1 reference

Europe PubMed Central

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12 June 2020

3045-3060

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26840628%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Differential effect of amylin on endothelial-dependent vasodilation in mesenteric arteries from control and insulin resistant rats

1 reference

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7 September 2018

FM19G11 reverses endothelial dysfunction in rat and human arteries through stimulation of the PI3K/Akt/eNOS pathway, independently of mTOR/HIF-1α activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Arginase inhibition restores endothelial function in diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-uncoupling in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Preserved endothelial function in human obesity in the absence of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Insulin resistance and not BMI is the major determinant of early vascular impairment in patients with morbid obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Arginase: the emerging therapeutic target for vascular oxidative stress and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Arginase inhibition alleviates hypertension in the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

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Asymmetric dimethylarginine plasma levels and endothelial function in newly diagnosed type 2 diabetic patients

1 reference

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Arginase II Promotes Macrophage Inflammatory Responses Through Mitochondrial Reactive Oxygen Species, Contributing to Insulin Resistance and Atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Positive crosstalk between arginase-II and S6K1 in vascular endothelial inflammation and aging

1 reference

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7 September 2018

Insulin resistance and coronary heart disease in nondiabetic individuals

1 reference

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The effect of antihypertensive drugs on endothelial function as assessed by flow-mediated vasodilation in hypertensive patients

1 reference

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Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

In vivo nitric oxide synthesis, insulin sensitivity, and asymmetric dimethylarginine in obese subjects without and with metabolic syndrome.

1 reference

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7 September 2018

Effects of pioglitazone and metformin on vascular endothelial function in patients with type 2 diabetes treated with sulfonylureas.

1 reference

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7 September 2018

Insulin resistance: the link between obesity and cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Weight loss improves endothelial function independently of ADMA reduction in severe obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

L-arginine, NO and asymmetrical dimethylarginine in hypertension and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Vascular endothelial-specific dimethylarginine dimethylaminohydrolase-1-deficient mice reveal that vascular endothelium plays an important role in removing asymmetric dimethylarginine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Role of the PRMT-DDAH-ADMA axis in the regulation of endothelial nitric oxide production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Endothelial dysfunction, ADMA and insulin resistance in essential hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Asymmetric dimethylarginine levels and carotid intima-media thickness in obese patients with polycystic ovary syndrome and their relationship to metabolic parameters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Reduced EDHF responses and connexin activity in mesenteric arteries from the insulin-resistant obese Zucker rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Insulin resistance functionally limits endothelium-dependent coronary vasodilation in nondiabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Insulin reduces plasma arginase activity in type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Arginase: a critical regulator of nitric oxide synthesis and vascular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

The clinical significance of asymmetric dimethylarginine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Plasma asymmetric dimethylarginine concentrations are elevated in obese insulin-resistant women and fall with weight loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover

1 reference

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Intensive insulin therapy protects the endothelium of critically ill patients

1 reference

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Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension

1 reference

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Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality?

1 reference

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Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, explains the "L-arginine paradox" and acts as a novel cardiovascular risk factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

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Use and abuse of HOMA modeling

1 reference

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Early and intermediate Amadori glycosylation adducts, oxidative stress, and endothelial dysfunction in the streptozotocin-induced diabetic rats vasculature

1 reference

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7 September 2018

Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor

1 reference

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7 September 2018

Insulin resistance quantification by fasting insulin plasma values and HOMA index in a non-diabetic population

1 reference

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7 September 2018

Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887698

7 September 2018

Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases

1 reference

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7 September 2018

EDHF-mediated relaxation is impaired in fructose-fed rats.

1 reference

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Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

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Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

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Diabetes and ageing-induced vascular inflammation

1 reference

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Association between insulin resistance and endothelial dysfunction in type 2 diabetes and the effects of pioglitazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/26840628

12 December 2020

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Serum asymmetric dimethylarginine and nitric oxide levels in obese postmenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/26840628

12 December 2020

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inferred from PubMed ID database lookup

Serum fetuin-A and arginase-1 in human obesity model: Is there any interaction between inflammatory status and arginine metabolism?

1 reference

https://pubmed.ncbi.nlm.nih.gov/26840628

12 December 2020

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Impairment of Endothelium-Dependent Relaxation by Increasing Percentages of Glycosylated Human Hemoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/26840628

12 December 2020

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inferred from PubMed ID database lookup

Endothelial Dysfunction, Obesity and Insulin Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/26840628

12 December 2020

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inferred from PubMed ID database lookup

Atorvastatin modulates the DDAH1/ADMA system in high-fat diet-induced insulin-resistant rats with endothelial dysfunction

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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