(Q53833977)

English

Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism

scientific article published on March 5, 1992

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Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism (English)

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Robert Lefkowitz

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Lefkowitz RJ

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Caron MG

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S. B. Liggett

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J. Ostrowski

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L. C. Chesnut

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H. Kurose

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J. R. Raymond

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M. G. Caron

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R. J. Lefkowitz

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1 March 1992

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5 March 1992

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Journal of Biological Chemistry

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Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization

2

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Molecular Pharmacology

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39

192

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Campbell

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1991

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1 December 2023

Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity

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10.1016/S0021-9258(18)42894-3

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1 December 2023

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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10.1016/S0021-9258(18)42894-3

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Molecular Pharmacology

12

36

641

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Liggett

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1989

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Molecular Pharmacology

13

32

258

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McKernan

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1987

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1 December 2023

Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase

16

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10.1016/S0021-9258(18)42894-3

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1 December 2023

Journal of Pharmacology and Experimental Therapeutics

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233

433

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Villeneuve

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1985

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Molecular Pharmacology

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29

1

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Motulsky

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1986

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1 December 2023

Selective down-regulation of adrenergic receptor subtypes in tissues from rats with pheochromocytoma

21

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10.1016/S0021-9258(18)42894-3

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1 December 2023

Effects of combined administration of imipramine and chlorpromazine on β- and α2-adrenergic receptors in rat cerebral cortex

22

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10.1016/S0021-9258(18)42894-3

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1 December 2023

Molecular Pharmacology

23

21

36

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Karliner

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1982

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Journal of Pharmacology and Experimental Therapeutics

24

254

294

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Jones

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1990

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1 December 2023

Agonist-induced down-regulation of muscarinic cholinergic and alpha 2-adrenergic receptors after inactivation of Ni by pertussis toxin.

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In vitro and in vivo down-regulation of human platelet alpha 2-adrenoceptors by clonidine

26

1 reference

10.1016/S0021-9258(18)42894-3

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1 December 2023

Journal of Pharmacology and Experimental Therapeutics

27

224

1

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Aarons

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1983

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1 December 2023

Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

29

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10.1016/S0021-9258(18)42894-3

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1 December 2023

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Europe PubMed Central

20 May 2018

http://europepmc.org/abstract/MED/1311318

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