(Q53837214)

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Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial.

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scholarly article

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Europe PubMed Central

20 May 2018

http://europepmc.org/abstract/PMC/5885175

Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial. (English)

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Europe PubMed Central

20 May 2018

http://europepmc.org/abstract/PMC/5885175

phase II clinical trial

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Toshihiko Doi

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20 May 2018

http://europepmc.org/abstract/PMC/5885175

Charles S. Fuchs

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Charles S Fuchs

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Europe PubMed Central

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http://europepmc.org/abstract/PMC/5885175

Shadia I. Jalal

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Shadia I Jalal

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http://europepmc.org/abstract/PMC/5885175

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Yung-Jue Bang

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http://europepmc.org/abstract/PMC/5885175

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Atsushi Ohtsu

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http://europepmc.org/abstract/PMC/5885175

author name string

Raymond W Jang

3

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http://europepmc.org/abstract/PMC/5885175

Kei Muro

4

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http://europepmc.org/abstract/PMC/5885175

Taroh Satoh

5

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http://europepmc.org/abstract/PMC/5885175

Manuela Machado

6

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http://europepmc.org/abstract/PMC/5885175

Weijing Sun

7

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http://europepmc.org/abstract/PMC/5885175

Manish A Shah

9

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http://europepmc.org/abstract/PMC/5885175

Jean-Phillipe Metges

10

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http://europepmc.org/abstract/PMC/5885175

Marcelo Garrido

11

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http://europepmc.org/abstract/PMC/5885175

Talia Golan

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http://europepmc.org/abstract/PMC/5885175

Mario Mandala

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http://europepmc.org/abstract/PMC/5885175

Zev A Wainberg

14

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http://europepmc.org/abstract/PMC/5885175

Daniel V Catenacci

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http://europepmc.org/abstract/PMC/5885175

Kohei Shitara

17

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Ravit Geva

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http://europepmc.org/abstract/PMC/5885175

Jonathan Bleeker

19

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http://europepmc.org/abstract/PMC/5885175

Andrew H Ko

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http://europepmc.org/abstract/PMC/5885175

Geoffrey Ku

21

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http://europepmc.org/abstract/PMC/5885175

Philip Philip

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http://europepmc.org/abstract/PMC/5885175

Peter C Enzinger

23

1 reference

Europe PubMed Central

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http://europepmc.org/abstract/PMC/5885175

Diane Levitan

25

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http://europepmc.org/abstract/PMC/5885175

Jiangdian Wang

26

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Minori Rosales

27

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Rita P Dalal

28

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Harry H Yoon

29

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publication date

15 March 2018

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http://europepmc.org/abstract/PMC/5885175

1 reference

Europe PubMed Central

20 May 2018

http://europepmc.org/abstract/PMC/5885175

Third-line systemic treatment versus best supportive care for advanced/metastatic gastric cancer: A systematic review and meta-analysis.

1 reference

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IFN-γ-related mRNA profile predicts clinical response to PD-1 blockade.

1 reference

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22 May 2018

New agents on the horizon in gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Safety and activity of pembrolizumab in patients with locally advanced or metastatic urothelial cancer (KEYNOTE-012): a non-randomised, open-label, phase 1b study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Pembrolizumab for patients with melanoma or non-small-cell lung cancer and untreated brain metastases: early analysis of a non-randomised, open-label, phase 2 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Pembrolizumab for patients with PD-L1-positive advanced gastric cancer (KEYNOTE-012): a multicentre, open-label, phase 1b trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Abundant PD-L1 expression in Epstein-Barr Virus-infected gastric cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Pembrolizumab in Patients With Advanced Triple-Negative Breast Cancer: Phase Ib KEYNOTE-012 Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Immune checkpoints aberrations and gastric cancer; assessment of prognostic value and evaluation of therapeutic potentials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Global cancer statistics, 2012

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Comprehensive molecular characterization of gastric adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Survival advantage for irinotecan versus best supportive care as second-line chemotherapy in gastric cancer--a randomised phase III study of the Arbeitsgemeinschaft Internistische Onkologie (AIO).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Global cancer statistics

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Chemotherapy for advanced gastric cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteria

1 reference

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22 May 2018

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

22 May 2018

Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

13 August 2018

Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

13 August 2018

Randomized, open-label, phase III study comparing irinotecan with paclitaxel in patients with advanced gastric cancer without severe peritoneal metastasis after failure of prior combination chemotherapy using fluoropyrimidine plus platinum: WJOG 400

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

13 August 2018

Salvage chemotherapy for pretreated gastric cancer: a randomized phase III trial comparing chemotherapy plus best supportive care with best supportive care alone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5885175

13 August 2018

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†

1 reference

https://pubmed.ncbi.nlm.nih.gov/29543932

12 December 2020

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Identifiers

10.1001/JAMAONCOL.2018.0013

1 reference

Europe PubMed Central

20 May 2018

http://europepmc.org/abstract/PMC/5885175

1 reference

Europe PubMed Central

20 May 2018

http://europepmc.org/abstract/PMC/5885175

1 reference

Europe PubMed Central

20 May 2018

http://europepmc.org/abstract/PMC/5885175

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