(Q53845593)

20 May 2018

title

L-Dopa stimulates expression of the antioxidant enzyme NAD(P)H:quinone oxidoreductase (NQO) in cultured astroglial cells. (English)

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20 May 2018

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van Muiswinkel FL

1

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20 May 2018

Riemers FM

2

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20 May 2018

Peters GJ

3

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20 May 2018

LaFleur MV

4

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20 May 2018

Siegel D

5

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20 May 2018

Jongenelen CA

6

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20 May 2018

Drukarch B

7

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20 May 2018

publication date

1 September 2000

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20 May 2018

Free Radical Biology and Medicine

published in

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20 May 2018

volume

29

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20 May 2018

issue

5

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20 May 2018

page(s)

442-453

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20 May 2018

L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress.

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Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency.

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Astrocyte-enhanced neuronal survival is mediated by scavenging of extracellular reactive oxygen species.

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Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

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Presence of glutathione immunoreactivity in cultured neurones and astrocytes.

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Toxic and protective effects of L-dopa on mesencephalic cell cultures

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Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism

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The oxidative metabolism of catecholamines in the brain: a review

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Distribution of DT diaphorase in the rat brain: biochemical and immunohistochemical studies

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Histochemical detection of quinone reductase activity in situ using LY 83583 reduction and oxidation.

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Chemical and molecular regulation of enzymes that detoxify carcinogens

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Differentiated rat glial cell strain in tissue culture.

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Glutathione is involved in the granular storage of dopamine in rat PC 12 pheochromocytoma cells: implications for the pathogenesis of Parkinson's disease.

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7 January 2021

The nucleotide sequence of the rat cytoplasmic β–actin gene

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7 January 2021

Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: A screening assay for anticarcinogenic enzyme inducers

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7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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7 January 2021

Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling

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7 January 2021

Transfection of COS-1 cells with DT-diaphorase cDNA: role of a base change at position 609

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7 January 2021

Neurotoxicity of levodopa on catecholamine-rich neurons

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7 January 2021

Immunohistochemical localization of carbonyl reductase in human tissues

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7 January 2021

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7 January 2021

Antioxidant response element

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7 January 2021

On the antioxidant effects of ascorbic acid and glutathione

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7 January 2021

The rat quinone reductase antioxidant response element. Identification of the nucleotide sequence required for basal and inducible activity and detection of antioxidant response element-binding proteins in hepatoma and non-hepatoma cell lines

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7 January 2021

Levodopa toxicity in foetal rat midbrain neurones in culture: modulation by ascorbic acid.

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7 January 2021

Levodopa therapy and survival in idiopathic Parkinson's disease: Olmsted County project

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7 January 2021

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7 January 2021

Chronic levodopa is not toxic for remaining dopamine neurons, but instead promotes their recovery, in rats with moderate nigrostriatal lesions

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7 January 2021

Metabolic coupling between glia and neurons.

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7 January 2021

Astrocytes protect neurons from hydrogen peroxide toxicity

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7 January 2021

Assessment of the role of the glutathione and pentose phosphate pathways in the protection of primary cerebrocortical cultures from oxidative stress

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7 January 2021

Anethole dithiolethione, a putative neuroprotectant, increases intracellular and extracellular glutathione levels during starvation of cultured astroglial cells

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7 January 2021

Maintenance of neuronal glutathione by glial cells

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7 January 2021

Superoxide dismutase and catalase prevent the formation of reactive oxygen species during reduction of cyclized dopa ortho-quinone by DT-diaphorase

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7 January 2021

The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems

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7 January 2021

The reduction of alpha-tocopherolquinone by human NAD(P)H: quinone oxidoreductase: the role of alpha-tocopherolhydroquinone as a cellular antioxidant

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7 January 2021

Drug treatment of Parkinson's disease. Time for phase II

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7 January 2021

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Identifiers

DOI

1 reference

20 May 2018

release_c3ojqokotncyvaawgjhbkj23ga

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/c3ojqokotncyvaawgjhbkj23ga

24 November 2022

mapped directly with Wikidata item

PubMed ID

11020666

1 reference

20 May 2018