(Q53855022)

21 May 2018

title

The inhibitory gamma subunit of the rod cGMP phosphodiesterase binds the catalytic subunits in an extended linear structure. (English)

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21 May 2018

author name string

Lian-Wang Guo

1

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21 May 2018

Hakim Muradov

2

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21 May 2018

Abdol R Hajipour

3

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21 May 2018

Michael K Sievert

4

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21 May 2018

Nikolai O Artemyev

5

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21 May 2018

Arnold E Ruoho

6

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21 May 2018

language of work or name

English

0 references

publication date

4 April 2006

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21 May 2018

Journal of Biological Chemistry

published in

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21 May 2018

volume

281

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21 May 2018

issue

22

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21 May 2018

page(s)

15412-15422

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21 May 2018

G proteins and phototransduction.

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The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory gamma subunit

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cGMP signaling in vertebrate retinal photoreceptor cells

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Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

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Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness

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Mutation in rod PDE6 linked to congenital stationary night blindness impairs the enzyme inhibition by its gamma-subunit

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Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase

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The positive role of the carboxyl terminus of the gamma subunit of retinal cGMP-phosphodiesterase in maintaining phosphodiesterase activity in vivo

21 January 2018

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Three-dimensional structure of non-activated cGMP phosphodiesterase 6 and comparison of its image with those of activated forms

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The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding

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Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The N terminus of GTP gamma S-activated transducin alpha-subunit interacts with the C terminus of the cGMP phosphodiesterase gamma-subunit

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Further definition of the substance P (SP)/neurokinin-1 receptor complex. MET-174 is the site of photoinsertion p-benzoylphenylalanine4 SP.

21 January 2018

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Real time conformational changes in the retinal phosphodiesterase gamma subunit monitored by resonance energy transfer.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600595200

21 January 2018

Identifiers

DOI

10.1074/JBC.M600595200

1 reference

21 May 2018

PubMed ID

16595671

1 reference

21 May 2018