(Q53871899)

21 May 2018

title

Immunoglobulin-free light chains elicit immediate hypersensitivity-like responses. (English)

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21 May 2018

author

Takashi Saito

9

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21 May 2018

Andries S Koster

object named as

Andries S Koster

12

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Frans P. Nijkamp

13

object named as

Frans P Nijkamp

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21 May 2018

Johan Garssen

5

object named as

Johan Garssen

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21 May 2018

author name string

Frank A Redegeld

1

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21 May 2018

Maurice W van der Heijden

2

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21 May 2018

Mirjam Kool

3

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21 May 2018

Bianca M Heijdra

4

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21 May 2018

Aletta D Kraneveld

6

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21 May 2018

Henk Van Loveren

7

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21 May 2018

Paul Roholl

8

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21 May 2018

J Sjef Verbeek

10

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21 May 2018

Jill Claassens

11

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21 May 2018

language of work or name

English

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publication date

17 June 2002

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21 May 2018

published in

Nature Medicine

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21 May 2018

volume

8

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21 May 2018

issue

7

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21 May 2018

page(s)

694-701

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21 May 2018

https://scigraph.springernature.com/pub.10.1038/nm722

exact match

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cites work

Induction and regulation of the IgE response

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Active anaphylaxis in IgE-deficient mice

21 January 2018

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Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis

21 January 2018

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Immune serum from mice contact-sensitized with picryl chloride contains an antigen-specific T cell factor that transfers immediate cutaneous reactivity.

21 January 2018

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The renal handling of low molecular weight proteins. II. Disorders of serum protein catabolism in patients with tubular proteinuria, the nephrotic syndrome, or uremia

21 January 2018

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A simpler sort of antibody

21 January 2018

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Contributions of heavy and light chains of rabbit immunoglobulin G to antibody activity. I. Binding studies on isolated heavy and light chains

21 January 2018

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Monoclonal antibody light chain with prothrombinase activity

21 January 2018

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A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

21 January 2018

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IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions

21 January 2018

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IgE antibody up-regulates high affinity IgE binding on murine bone marrow-derived mast cells.

21 January 2018

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Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes

21 January 2018

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Localization of a single binding site for immunoglobulin light chains on human Tamm-Horsfall glycoprotein

21 January 2018

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Required early complement activation in contact sensitivity with generation of local C5-dependent chemotactic activity, and late T cell interferon gamma: a possible initiating role of B cells

21 January 2018

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FcR gamma chain deletion results in pleiotrophic effector cell defects

21 January 2018

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Paired immunoglobulin-like receptor (PIR)-A is involved in activating mast cells through its association with Fc receptor gamma chain

21 January 2018

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Stimulatory function of gp49A, a murine Ig-like receptor, in rat basophilic leukemia cells

21 January 2018

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Antibodies against human CD63 activate transfected rat basophilic leukemia (RBL-2H3) cells

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Mast cells control neutrophil recruitment during T cell-mediated delayed-type hypersensitivity reactions through tumor necrosis factor and macrophage inflammatory protein 2.

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Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis

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Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion

21 January 2018

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Elevated mast cell tryptase in cerebrospinal fluid of multiple sclerosis patients

21 January 2018

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Synthesis of Excess Light Chains of Gamma Globulin by Rabbit Lymph Node Cells

21 January 2018

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Relative Rates of Synthesis of Immunoglobulins and Light Chains in Rabbit Spleen Cells during Secondary Response

21 January 2018

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Critical protective role of mast cells in a model of acute septic peritonitis

21 January 2018

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Evidence by radioimmunoassay that mitogen-activated human blood mononuclear cells secrete significant amounts of light chain Ig unassociated with heavy chain

21 January 2018

1 reference

7 January 2021

Specific Binding Activity of Isolated Light Chains of Antibodies

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7 January 2021

An immunoglobulin light chain dimer with CD4 antigen specificity

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7 January 2021

Binding of 2,4-dinitrophenyl derivatives by the light chain dimer obtained from immunoglobulin A produced by MOPC-315 mouse myeloma

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7 January 2021

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7 January 2021

Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival

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7 January 2021

Regulation of mast cell survival by IgE

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7 January 2021

Free kappa and lambda light chain levels in the cerebrospinal fluid of patients with multiple sclerosis and other neurological diseases

1 reference

7 January 2021

Free light chains of immunoglobulins in serum from patients with rheumatoid arthritis, sarcoidosis, chronic infections and pulmonary cancer

1 reference

7 January 2021

Stem cell factor and interleukin-4 induce murine bone marrow cells to develop into mast cells with connective tissue type characteristics in vitro

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM722

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21 May 2018

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21 May 2018