(Q54057730)

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Mechanism by which phosphonoformic acid resistance mutations restore 3'-azido-3'-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase.

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

Mechanism by which phosphonoformic acid resistance mutations restore 3'-azido-3'-deoxythymidine (AZT) sensitivity to AZT-resistant HIV-1 reverse transcriptase. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

1 reference

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Arion D

1

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

Sluis-Cremer N

2

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

Parniak MA

3

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

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publication date

1 March 2000

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

275

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Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

13

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

9251-9255

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)

1 reference

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21 January 2018

Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Site-specific mutagenesis of AIDS virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Characterisation of foscarnet-resistant strains of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Enhanced binding of azidothymidine-resistant human immunodeficiency virus 1 reverse transcriptase to the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Functional analysis of amino acid residues constituting the dNTP binding pocket of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.13.9251

21 January 2018

Identifiers

10.1074/JBC.275.13.9251

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 May 2018

http://europepmc.org/abstract/MED/10734063

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