(Q54074532)

24 May 2018

title

Synthesis and binding properties of photoactivable biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein. (English)

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24 May 2018

1 reference

Teodori E

1

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24 May 2018

Ettori D

2

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24 May 2018

Garnier-Suillerot A

3

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24 May 2018

Gualtieri F

4

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24 May 2018

Manetti D

5

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24 May 2018

Romanelli MN

6

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24 May 2018

Scapecchi S

7

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24 May 2018

language of work or name

English

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publication date

1 September 1999

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24 May 2018

Bioorganic & Medicinal Chemistry

published in

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24 May 2018

volume

7

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24 May 2018

issue

9

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24 May 2018

page(s)

1873-1880

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24 May 2018

Molecular mechanisms of multidrug resistance in cancer chemotherapy

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Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents

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N-(p-azido-3-[125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cells

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A New Paclitaxel Photoaffinity Analog with a 3-(4-Benzoylphenyl)propanoyl Probe for Characterization of Drug-Binding Sites on Tubulin and P-Glycoprotein

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Study of P-glycoprotein functionality in living resistant K562 cells after photolabeling with a verapamil analogue

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Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil

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7 January 2021

Reversal of multidrug resistance by verapamil analogues.

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Novel phenoxyalkylamine derivatives. II. Synthesis and Ca2+-antagonistic activities of alpha-alkyl-alpha-[(phenoxypropylamino)propyl]benzeneacetonit rile derivatives

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Synthesis and biological actions of highly potent and prolonged acting biotin-labeled melanotropins.

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Determination of the osmotic active drug concentration in the cytoplasm of anthracycline-resistant and -sensitive K562 cells

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Comparison of the membrane transport of anthracycline derivatives in drug-resistant and drug-sensitive K562 cells

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Correlation between the short-term measurements of drug accumulation in living cells and the long-term growth inhibition.

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The ability of verapamil to restore intracellular accumulation of anthracyclines in multidrug resistant cells depends on the kinetics of their uptake.

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7 January 2021

10.1016/S0968-0896(99)00104-2

Identifiers

DOI

1 reference

24 May 2018

PubMed ID

10530935

1 reference

24 May 2018