(Q54117923)

25 May 2018

http://europepmc.org/abstract/MED/29615789

title

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. (English)

1 reference

25 May 2018

http://europepmc.org/abstract/MED/29615789

author

Subhamoy Dasgupta

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Bokai Zhu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Bryan C Nikolai

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Xiang H-F Zhang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Charles E Foulds

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

13

Sophia Y Tsai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

14

Ming-Jer Tsai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Kimal Rajapakshe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Ping Yi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Nagireddy Putluri

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Jong Min Choi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Sung Y Jung

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Cristian Coarfa

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Thomas F Westbrook

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Bert W O'Malley

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

3 April 2018

1 reference

25 May 2018

http://europepmc.org/abstract/MED/29615789

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

556

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

7700

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

249-254

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/s41586-018-0018-1

9 June 2020

exact match

0 references

cites work

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A Cell-Autonomous Mammalian 12 hr Clock Coordinates Metabolic and Stress Rhythms.

25 August 2018

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Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

25 August 2018

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A Novel [15N] Glutamine Flux using LC-MS/MS-SRM for Determination of Nucleosides and Nucleobases

25 August 2018

1 reference

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mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

25 August 2018

1 reference

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HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

The pentose phosphate pathway and cancer

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Transcriptional coregulators: emerging roles of SRC family of coactivators in disease pathology

25 August 2018

1 reference

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Quantitative flux analysis reveals folate-dependent NADPH production.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Nuclear receptor coactivators: master regulators of human health and disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Cancer cell metabolism: there is no ROS for the weary.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines

25 August 2018

1 reference

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The role of SRC-3 in human breast cancer

25 August 2018

1 reference

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Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family

25 August 2018

1 reference

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Multi-modulation of nuclear receptor coactivators through posttranslational modifications

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Brick by brick: metabolism and tumor cell growth

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

The expanding cosmos of nuclear receptor coactivators

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Scaffold attachment factor SAFB1 suppresses estrogen receptor alpha-mediated transcription in part via interaction with nuclear receptor corepressor

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

25 August 2018

1 reference

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AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Mammalian 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a bifunctional enzyme that controls glycolysis.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a metabolic signaling enzyme

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Induction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA by refeeding and insulin.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5895503

10.1038/S41586-018-0018-1

30 November 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29615789%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference