(Q54192438)

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Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25200274%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25200274%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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Europe PubMed Central

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16 February 2020

Christopher B Little

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25200274%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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Miriam T Jackson

1

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Europe PubMed Central

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16 February 2020

Sanaa Zaki

3

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Europe PubMed Central

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16 February 2020

Margaret M Smith

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Europe PubMed Central

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16 February 2020

Sharon McCracken

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Europe PubMed Central

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16 February 2020

Susan M Smith

6

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Europe PubMed Central

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16 February 2020

Christopher J Jackson

7

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Europe PubMed Central

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16 February 2020

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1 December 2014

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Europe PubMed Central

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16 February 2020

Arthritis & Rheumatology

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Europe PubMed Central

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16 February 2020

66

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16 February 2020

12

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16 February 2020

3337-3348

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Europe PubMed Central

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16 February 2020

Osteoarthritis: a disease of the joint as an organ

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis -- results of a 1 year longitudinal arthroscopic study in 422 patients.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Clinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3-year, prospective EULAR study

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Presence of MRI-detected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

PARticipation in inflammation

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Immunomodulatory role of proteinase-activated receptor-2

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Expression of proteinase-activated receptors (PAR)-2 in articular chondrocytes is modulated by IL-1beta, TNF-alpha and TGF-beta

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Expression of protease-activated receptor-2 by osteoblasts.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Reduction of arthritis severity in protease-activated receptor-deficient mice.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Amelioration of collagen-induced arthritis by thrombin inhibition

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Effect of thrombin inhibition on synovial inflammation in antigen induced arthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Essential role for proteinase-activated receptor-2 in arthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Correlation of protease-activated receptor-2 expression and synovitis in rheumatoid and osteoarthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Proteinase-activated receptor-2 gene disruption limits the effect of osteoarthritis on cartilage in mice: a novel target in joint degradation

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Role of the thrombin receptor in development and evidence for a second receptor.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Delayed onset of inflammation in protease-activated receptor-2-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Activation of cartilage matrix metalloproteinases by activated protein C.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Proteinase-activated receptor-2 is required for normal osteoblast and osteoclast differentiation during skeletal growth and repair.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

The role of protease-activated receptor-1 in bone healing.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Studies on the receptors mediating responses of osteoblasts to thrombin.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Sclerostin is expressed in articular cartilage but loss or inhibition does not affect cartilage remodeling during aging or following mechanical injury

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Lentiviral small hairpin RNA knockdown of macrophage inflammatory protein-1γ ameliorates experimentally induced osteoarthritis in mice

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Protease-activated receptor-1 regulates cytokine production and induces the suppressor of cytokine signaling-3 in microglia.

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Gene and locus structure and chromosomal localization of the protease-activated receptor gene family

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Expression of protease-activated receptor (PAR)-2, but not other PARs, is regulated by inflammatory cytokines in rat astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Novel animal models of acute and chronic cancer pain: a pivotal role for PAR2

1 reference

https://api.crossref.org/works/10.1002%2FART.38876

21 January 2018

Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial

1 reference

30 December 2023

https://opencitations.net/index/api/v1/citations/10.3899/JRHEUM.130199

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