(Q54195456)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25104317%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

Overexpression of a dominant-negative mutant of SIRT1 in mouse heart causes cardiomyocyte apoptosis and early-onset heart failure (English)

1 reference

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12 March 2020

0 references

1 reference

3

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12 March 2020

author name string

WenLi Mu

1

1 reference

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12 March 2020

QingJun Zhang

2

1 reference

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12 March 2020

WenYan Fu

4

1 reference

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12 March 2020

Wei Zheng

5

1 reference

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12 March 2020

YunBiao Lu

6

1 reference

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12 March 2020

HongLiang Li

7

1 reference

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12 March 2020

YuSheng Wei

8

1 reference

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12 March 2020

Li Li

9

1 reference

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12 March 2020

ZhiGang She

10

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12 March 2020

HouZao Chen

11

1 reference

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12 March 2020

DePei Liu

12

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12 March 2020

publication date

7 August 2014

1 reference

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Science in China. Series C: Life Sciences

12 March 2020

published in

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12 March 2020

volume

57

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12 March 2020

issue

9

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12 March 2020

page(s)

915-924

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https://scigraph.springernature.com/pub.10.1007/s11427-014-4687-1

12 March 2020

exact match

0 references

cites work

The molecular biology of the SIR proteins

1 reference

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Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

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Negative control of p53 by Sir2alpha promotes cell survival under stress

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Calorie restriction--the SIR2 connection

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Franklin H. Epstein Lecture: Sirtuins, aging, and medicine

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Mammalian sirtuins: biological insights and disease relevance

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Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.

21 January 2018

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Sirt1 protects against high-fat diet-induced metabolic damage

21 January 2018

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Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain.

21 January 2018

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Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

21 January 2018

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SIRT1 controls endothelial angiogenic functions during vascular growth

21 January 2018

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Ca2+/calmodulin-dependent protein kinase kinase β phosphorylation of Sirtuin 1 in endothelium is atheroprotective

21 January 2018

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Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

1 reference

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Vascular smooth muscle cell sirtuin 1 protects against DNA damage and inhibits atherosclerosis

21 January 2018

1 reference

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SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

21 January 2018

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SIRT1 acts as a modulator of neointima formation following vascular injury in mice.

21 January 2018

1 reference

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Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes

21 January 2018

1 reference

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Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

21 January 2018

1 reference

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SIRT1 mediates the protective function of Nkx2.5 during stress in cardiomyocytes

21 January 2018

1 reference

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Sirt1 regulates aging and resistance to oxidative stress in the heart

21 January 2018

1 reference

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PPARα-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathway.

21 January 2018

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Sirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in mice

21 January 2018

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Impact of caloric restriction on myocardial ischaemia/reperfusion injury and new therapeutic options to mimic its effects

21 January 2018

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Silent information regulator 1 protects the heart from ischemia/reperfusion

21 January 2018

1 reference

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SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

21 January 2018

1 reference

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Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction

21 January 2018

1 reference

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Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase

21 January 2018

1 reference

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SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells

21 January 2018

1 reference

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The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.

21 January 2018

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21 January 2018

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Overexpression of bone morphogenetic protein 10 in myocardium disrupts cardiac postnatal hypertrophic growth

21 January 2018

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Targeted cardiac overexpression of A20 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction

21 January 2018

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The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

21 January 2018

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A mechanistic role for cardiac myocyte apoptosis in heart failure

21 January 2018

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Acetylation is indispensable for p53 activation

21 January 2018

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PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

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Transcriptional upregulation of PUMA modulates endoplasmic reticulum calcium pool depletion-induced apoptosis via Bax activation

21 January 2018

1 reference

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