(Q54228570)

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The microRNA Machinery.

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scholarly article

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

The microRNA Machinery. (English)

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

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Thomas C Roberts

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

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1 January 2015

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Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

Advances in Experimental Medicine and Biology

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

887

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

15-30

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

Post-transcriptional gene silencing by siRNAs and miRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Therapeutic targeting of non-coding RNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Loss of miR-29 in myoblasts contributes to dystrophic muscle pathogenesis

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Circulating microRNAs as stable blood-based markers for cancer detection

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Serum microRNAs are promising novel biomarkers

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

MicroRNA genes are transcribed by RNA polymerase II

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Processing of intronic microRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Identification of novel genes coding for small expressed RNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

MicroRNA maturation: stepwise processing and subcellular localization

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Specificity of microRNA target selection in translational repression

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Mammalian microRNAs predominantly act to decrease target mRNA levels

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The MicroRNA Biology of the Mammalian Nucleus

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The Microprocessor complex mediates the genesis of microRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Human RNase III is a 160-kDa protein involved in preribosomal RNA processing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The nuclear RNase III Drosha initiates microRNA processing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Short interfering RNA-mediated knockdown of drosha and pasha in undifferentiated Meloidogyne incognita eggs leads to irregular growth and embryonic lethality.

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Role for a bidentate ribonuclease in the initiation step of RNA interference

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The Drosha-DGCR8 complex in primary microRNA processing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

DiGeorge syndrome: part of CATCH 22.

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Processing of primary microRNAs by the Microprocessor complex

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Solution structure of the Drosha double-stranded RNA-binding domain

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Crystal structure of human DGCR8 core

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structure of the dimerization domain of DiGeorge Critical Region 8

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Heme is involved in microRNA processing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Nuclear export of microRNA precursors

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Exportin-5 mediates nuclear export of minihelix-containing RNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Terminal minihelix, a novel RNA motif that directs polymerase III transcripts to the cell cytoplasm. Terminal minihelix and RNA export.

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

A high-resolution structure of the pre-microRNA nuclear export machinery

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Ribonuclease activity and RNA binding of recombinant human Dicer

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Complexity of murine cardiomyocyte miRNA biogenesis, sequence variant expression and function

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Dicer is essential for mouse development

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Stem cell division is regulated by the microRNA pathway

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Single processing center models for human Dicer and bacterial RNase III

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structural basis for double-stranded RNA processing by Dicer

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Human let-7 stem-loop precursors harbor features of RNase III cleavage products

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structural determinants of RNA recognition and cleavage by Dicer

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structure of the human Dicer-TRBP complex by electron microscopy

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structural insights into RNA processing by the human RISC-loading complex

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The molecular architecture of human Dicer

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Dicer recognizes the 5' end of RNA for efficient and accurate processing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Argonaute2, a link between genetic and biochemical analyses of RNAi

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Functional siRNAs and miRNAs Exhibit Strand Bias

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Asymmetry in the assembly of the RNAi enzyme complex

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

let-7 regulates Dicer expression and constitutes a negative feedback loop

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Most mammalian mRNAs are conserved targets of microRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

A microRNA in a multiple-turnover RNAi enzyme complex

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

MicroRNA-directed cleavage of HOXB8 mRNA

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Relief of microRNA-mediated translational repression in human cells subjected to stress

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Repression of protein synthesis by miRNAs: how many mechanisms?

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Combinatorial microRNA target predictions

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Argonaute2 is the catalytic engine of mammalian RNAi

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The evolutionary journey of Argonaute proteins

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Purified Argonaute2 and an siRNA form recombinant human RISC

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Molecular dissection of human Argonaute proteins by DNA shuffling.

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Argonaute2 is essential for mammalian gastrulation and proper mesoderm formation

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation.

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The Crystal Structure of Human Argonaute2

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

The Structure of Human Argonaute-2 in Complex with miR-20a

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

A role for the P-body component GW182 in microRNA function

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-22380-3_2

21 January 2018

Identifiers

10.1007/978-3-319-22380-3_2

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

1 reference

Europe PubMed Central

26 May 2018

http://europepmc.org/abstract/MED/26662984

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