(Q34310927)

1 August 2017

title

The loop position of shRNAs and pre-miRNAs is critical for the accuracy of dicer processing in vivo (English)

1 reference

1 August 2017

Paul N Valdmanis

6

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author name string

Shuo Gu

1

1 reference

1 August 2017

Lan Jin

2

1 reference

1 August 2017

Yue Zhang

3

1 reference

1 August 2017

Yong Huang

4

1 reference

1 August 2017

Feijie Zhang

5

1 reference

1 August 2017

Mark A Kay

7

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1 August 2017

language of work or name

English

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publication date

1 November 2012

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1 August 2017

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1 August 2017

volume

151

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1 August 2017

issue

4

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1 August 2017

page(s)

900-911

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In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs

1 August 2017

cites work

1 reference

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The molecular architecture of human Dicer

6 July 2018

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6 July 2018

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The effects of stem length and core placement on shRNA activity

6 July 2018

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Dicer recognizes the 5' end of RNA for efficient and accurate processing

6 July 2018

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A 5'-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation.

6 July 2018

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Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes

6 July 2018

1 reference

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EGO-1, a C. elegans RdRP, modulates gene expression via production of mRNA-templated short antisense RNAs

6 July 2018

1 reference

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Dicer's helicase domain discriminates dsRNA termini to promote an altered reaction mode

6 July 2018

1 reference

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay

6 July 2018

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6 July 2018

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Structural basis of microRNA length variety.

6 July 2018

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A comprehensive survey of 3' animal miRNA modification events and a possible role for 3' adenylation in modulating miRNA targeting effectiveness

6 July 2018

1 reference

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Target RNA-directed trimming and tailing of small silencing RNAs

6 July 2018

1 reference

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Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

How do miRNAs mediate translational repression?

6 July 2018

1 reference

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Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

6 July 2018

1 reference

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Biochemical principles of small RNA pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Origins and Mechanisms of miRNAs and siRNAs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Biogenesis of small RNAs in animals

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Most mammalian mRNAs are conserved targets of microRNAs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Autoinhibition of human dicer by its internal helicase domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

RNA sequence analysis defines Dicer's role in mouse embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Strategies for silencing human disease using RNA interference

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

The colorectal microRNAome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Structural basis for double-stranded RNA processing by Dicer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Single processing center models for human Dicer and bacterial RNase III

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

A resource for large-scale RNA-interference-based screens in mammals.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

MicroRNAs: genomics, biogenesis, mechanism, and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Prediction of mammalian microRNA targets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Functional siRNAs and miRNAs Exhibit Strand Bias

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Asymmetry in the assembly of the RNAi enzyme complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Gene silencing using micro-RNA designed hairpins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

A system for stable expression of short interfering RNAs in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Argonaute2, a link between genetic and biochemical analyses of RNAi

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Molecular biology. Use and abuse of RNAi to study mammalian gene function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Turning Dicer on its head.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Recognition of the pre-miRNA structure by Drosophila Dicer-1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Structural determinants of RNA recognition and cleavage by Dicer

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

Synthetic shRNAs as potent RNAi triggers.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

RNA interference in adult mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3499986

10.1016/J.CELL.2012.09.042

28 October 2018

Identifiers

DOI

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1 August 2017

1 reference

1 August 2017

1 reference