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How do miRNAs mediate translational repression?
scientific article published on 7 May 2010
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scholarly article
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Europe PubMed Central
PMCID
2881910
retrieved
24 September 2017
editorial
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title
How do miRNAs mediate translational repression?
(English)
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stated in
Europe PubMed Central
PMCID
2881910
retrieved
24 September 2017
author name string
Shuo Gu
series ordinal
1
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Europe PubMed Central
PMCID
2881910
retrieved
24 September 2017
Mark A Kay
series ordinal
2
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stated in
Europe PubMed Central
PMCID
2881910
retrieved
24 September 2017
publication date
7 May 2010
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Europe PubMed Central
PMCID
2881910
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24 September 2017
published in
Silence: a journal of RNA regulation
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Europe PubMed Central
PMCID
2881910
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24 September 2017
volume
1
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Europe PubMed Central
PMCID
2881910
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24 September 2017
issue
1
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Europe PubMed Central
PMCID
2881910
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24 September 2017
page(s)
11
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Europe PubMed Central
PMCID
2881910
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24 September 2017
exact match
https://scigraph.springernature.com/pub.10.1186/1758-907x-1-11
0 references
cites work
Allosteric regulation of Argonaute proteins by miRNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Drosophila argonaute1 and argonaute2 employ distinct mechanisms for translational repression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Regulation of translation initiation in eukaryotes: mechanisms and biological targets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Origins and Mechanisms of miRNAs and siRNAs
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Essential and overlapping functions for mammalian Argonautes in microRNA silencing
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Widespread changes in protein synthesis induced by microRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
The impact of microRNAs on protein output
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Computational analysis of miRNA-mediated repression of translation: implications for models of translation initiation inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Widespread translational inhibition by plant miRNAs and siRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
MicroRNA-repressed mRNAs contain 40S but not 60S components
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
GW182 family proteins are crucial for microRNA-mediated gene silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
An mRNA m7G cap binding-like motif within human Ago2 represses translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
MicroRNA silencing through RISC recruitment of eIF6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Human let-7a miRNA blocks protein production on actively translating polyribosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Relief of microRNA-mediated translational repression in human cells subjected to stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
MicroRNAs direct rapid deadenylation of mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Short RNAs repress translation after initiation in mammalian cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Inhibition of translational initiation by Let-7 MicroRNA in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
The Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
24 September 2017
Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
17 June 2018
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
17 June 2018
Biochemical evidence for translational repression by Arabidopsis microRNAs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
19 August 2018
Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
19 August 2018
Evidence that microRNAs are associated with translating messenger RNAs in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
19 August 2018
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
19 August 2018
Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
19 August 2018
Recapitulation of short RNA-directed translational gene silencing in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881910
retrieved
4 November 2018
MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20459656
retrieved
12 December 2020
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Identifiers
DOI
10.1186/1758-907X-1-11
1 reference
stated in
Europe PubMed Central
PMCID
2881910
retrieved
24 September 2017
Dimensions Publication ID
1024535168
0 references
PMCID
2881910
1 reference
stated in
Europe PubMed Central
PMCID
2881910
retrieved
24 September 2017
PubMed ID
20459656
1 reference
stated in
Europe PubMed Central
PMCID
2881910
retrieved
24 September 2017
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