(Q54275721)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

GCN2 kinase is a key regulator of fibrogenesis and acute and chronic liver injury induced by carbon tetrachloride in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Elena Arriazu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Marina Ruiz de Galarreta

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

María J López-Zabalza

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Tung Ming Leung

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Natalia Nieto

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

publication date

14 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

published in

Laboratory Investigation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

93

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

303-310

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318883%20AND%20SRC:MED&resulttype=core&format=json

The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids

22 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

ATF4-dependent transcription mediates signaling of amino acid limitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Role of amino acids in the translational control of protein synthesis in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Activation of GCN2 in UV-irradiated cells inhibits translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Phosphorylation of eIF2α via the general control kinase, GCN2, modulates the ability of renal medullary cells to survive high urea stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Identification of GCN2 as new redox regulator for oxidative stress prevention in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Amino Acid Deprivation Decreases Intracellular Levels of Reactive Oxygen Species in Hepatic Stellate Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Hydrogen peroxide: a link between acetaldehyde-elicited alpha1(I) collagen gene up-regulation and oxidative stress in mouse hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Linking tRNA localization with activation of nutritional stress responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Functions of autophagy in hepatic and pancreatic physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

CCAAT/enhancer binding protein beta mediates the activation of the murine alpha1(I) collagen promoter by acetaldehyde

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Tumor necrosis factor alpha inhibits type I collagen synthesis through repressive CCAAT/enhancer-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Tumor necrosis factor alpha down-regulates expression of the alpha1(I) collagen gene in rat hepatic stellate cells through a p20C/EBPbeta- and C/EBPdelta-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Inhibition of collagen gene expression by interferon-gamma: novel role of the CCAAT/enhancer binding protein beta (C/EBPbeta).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

The roles of translation initiation regulation in ultraviolet light-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

7 January 2021

A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

7 January 2021

Leucine stimulates procollagen α1(I) translation on hepatic stellate cells through ERK and PI3K/Akt/mTOR activation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

7 January 2021

Regulation of type I collagen mRNA by amino acid deprivation in human lung fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.173

7 January 2021