(Q54283962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23147115%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects (English)

1 reference

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17 February 2020

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1 reference

Benedetta Maria Motta

4

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17 February 2020

Luca Valenti

8

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17 February 2020

Raffaela Rametta

1

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17 February 2020

Enrico Mozzi

2

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17 February 2020

author name string

P Dongiovanni

3

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17 February 2020

M Milano

5

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17 February 2020

G Roviaro

6

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17 February 2020

S Fargion

7

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17 February 2020

language of work or name

English

0 references

publication date

13 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23147115%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Obesity

17 February 2020

published in

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17 February 2020

volume

37

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17 February 2020

issue

7

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17 February 2020

page(s)

986-992

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https://scigraph.springernature.com/pub.10.1038/ijo.2012.181

17 February 2020

exact match

0 references

cites work

Nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Global burden of obesity in 2005 and projections to 2030.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.181

Liver fat in the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

The role of the lipogenic pathway in the development of hepatic steatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

The critical role of AKT2 in hepatic steatosis induced by PTEN loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

SREBPs suppress IRS-2-mediated insulin signalling in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Insulin inhibits transcription of IRS-2 gene in rat liver through an insulin response element (IRE) that resembles IREs of other insulin-repressed genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Enhancement in liver SREBP-1c/PPAR-alpha ratio and steatosis in obese patients: correlations with insulin resistance and n-3 long-chain polyunsaturated fatty acid depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

FoxO1 links hepatic insulin action to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

NOX4 pathway as a source of selective insulin resistance and responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Mechanisms by which carbohydrates regulate expression of genes for glycolytic and lipogenic enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Regulation of the expression of lipogenic enzyme genes by carbohydrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Glucose regulation of gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

SREBP-1c mediates the insulin-dependent hepatic glucokinase expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

Obesity and Heart Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

Induction of fatty-acid-synthase gene expression by glucose in primary culture of rat hepatocytes. Dependency upon glucokinase activity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.181

7 January 2021

Identifiers

DOI

10.1038/IJO.2012.181

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23147115%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference