(Q54320369)

27 May 2018

title

Diosgenin inhibits superoxide generation in FMLP-activated mouse neutrophils via multiple pathways. (English)

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27 May 2018

author name string

Y Lin

1

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27 May 2018

R Jia

2

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27 May 2018

Y Liu

3

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27 May 2018

Y Gao

4

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27 May 2018

X Zeng

5

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27 May 2018

J Kou

6

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27 May 2018

B Yu

7

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27 May 2018

publication date

18 October 2014

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27 May 2018

published in

Free Radical Research

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27 May 2018

volume

48

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27 May 2018

issue

12

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27 May 2018

page(s)

1485-1493

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27 May 2018

Targeting NADPH oxidases for the treatment of cancer and inflammation

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p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils

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DSM-RX78, a new phosphodiesterase inhibitor, suppresses superoxide anion production in activated human neutrophils and attenuates hemorrhagic shock-induced lung injury in rats.

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Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase.

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Diosgenin, a naturally occurring steroid, suppresses fatty acid synthase expression in HER2-overexpressing breast cancer cells through modulating Akt, mTOR and JNK phosphorylation

21 January 2018

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Anti-tumour and anti-oxidative potential of diosgenin against 7, 12-dimethylbenz(a)anthracene induced experimental oral carcinogenesis

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Diosgenin down-regulates NF-κB p65/p50 and p38MAPK pathways and attenuates acute lung injury induced by lipopolysaccharide in mice.

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Inhibition of TNF-α-induced adhesion molecule expression by diosgenin in mouse vascular smooth muscle cells via downregulation of the MAPK, Akt and NF-κB signaling pathways

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Protective effects of diosgenin in the hyperlipidemic rat model and in human vascular endothelial cells against hydrogen peroxide-induced apoptosis

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Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils

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Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN.

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Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions

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Activation of the A(3) adenosine receptor inhibits fMLP-induced Rac activation in mouse bone marrow neutrophils

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Diosgenin improves vascular function by increasing aortic eNOS expression, normalize dyslipidemia and ACE activity in chronic renal failure rats

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Akt Phosphorylates p47phoxand Mediates Respiratory Burst Activity in Human Neutrophils

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Cytosolic Phospholipase A2α–deficient Mice Are Resistant to Collagen-induced Arthritis

21 January 2018

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Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase

21 January 2018

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Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration

21 January 2018

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A p21-activated kinase-controlled metabolic switch up-regulates phagocyte NADPH oxidase

21 January 2018

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21 January 2018

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10.3109/10715762.2014.966705

21 January 2018

Identifiers

DOI

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27 May 2018

1 reference

27 May 2018