(Q54331486)

http://europepmc.org/abstract/PMC/4119716

27 May 2018

title

The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility. (English)

1 reference

http://europepmc.org/abstract/PMC/4119716

27 May 2018

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ciro Costagliola

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Marina Di Domenico

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Antonio Porcellini

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Erika Di Zazzo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Antonia Feola

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Candida Zuchegna

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Caterina F Donini

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

A Romano

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

R Frunzio

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

P Laccetti

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

9 July 2014

1 reference

http://europepmc.org/abstract/PMC/4119716

27 May 2018

published in

The Scientific World Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

565839

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

2 June 2020

copyright license

start time

1 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4119716/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Somatic mutations of PIK3R1 promote gliomagenesis

28 May 2018

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The p85α regulatory subunit of PI3K mediates cAMP-PKA and retinoic acid biological effects on MCF7 cell growth and migration

28 May 2018

1 reference

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28 May 2018

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Overexpression of 14-3-3ζ in cancer cells activates PI3K via binding the p85 regulatory subunit

28 May 2018

1 reference

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The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling

28 May 2018

1 reference

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Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulation

28 May 2018

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Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes

28 May 2018

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Insulin-sensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression

28 May 2018

1 reference

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Differential regulation of vascular smooth muscle and endothelial cell proliferation in vitro and in vivo by cAMP/PKA-activated p85alphaPI3K.

28 May 2018

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The influence of glucose-lowering therapies on cancer risk in type 2 diabetes

28 May 2018

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Risk of malignancies in patients with diabetes treated with human insulin or insulin analogues: a cohort study

28 May 2018

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Phosphoinositide 3-kinases in cell migration

28 May 2018

1 reference

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Association between phosphatidylinositol 3-kinase regulatory subunit p85alpha Met326Ile genetic polymorphism and colon cancer risk

28 May 2018

1 reference

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Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis

28 May 2018

1 reference

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p85 regulatory subunit of PI3K mediates cAMP-PKA and estrogens biological effects on growth and survival

28 May 2018

1 reference

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The negative regulation of phosphoinositide 3-kinase signaling by p85 and it's implication in cancer

28 May 2018

1 reference

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The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex

28 May 2018

1 reference

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Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

28 May 2018

1 reference

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PI3K/Akt and apoptosis: size matters

28 May 2018

1 reference

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Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

28 May 2018

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28 May 2018

1 reference

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Insulin receptor substrate-3 functions as transcriptional activator in the nucleus

28 May 2018

1 reference

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IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition

28 May 2018

1 reference

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cAMP signaling selectively influences Ras effectors pathways

28 May 2018

1 reference

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Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Novel functional PI 3-kinase antagonists inhibit cell growth and tumorigenicity in human cancer cell lines

28 May 2018

1 reference

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Phosphatidylinositol-3 kinase dependent pathways: the role in control of cell growth, survival, and malignant transformation.

28 May 2018

1 reference

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ErbB3 (HER3) interaction with the p85 regulatory subunit of phosphoinositide 3-kinase.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Pathophysiology of insulin resistance in human disease.

28 May 2018

1 reference

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Immunological demonstration of the accumulation of insulin, but not insulin receptors, in nuclei of insulin-treated cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Elevated insulin receptor content in human breast cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Results of continuous long-term intravenous application of octreotide via an implantable pump system in acromegaly resistant to operative and X-ray therapy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Colocalization of fluorescent markers in confocal microscope images of plant cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

SH3 domain of the phosphatidylinositol 3-kinase regulatory subunit is responsible for the formation of a sequestration complex with insulin receptor substrate-1.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4119716

Insulin-like growth factor I receptor signaling--overlapping or redundant pathways?

13 August 2018

1 reference

12 December 2020

Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle

1 reference

12 December 2020

The p85 regulatory subunit of PI3K mediates TSH-cAMP-PKA growth and survival signals

1 reference

12 December 2020

Insulin Receptor Substrate-1 is the Predominant Signaling Molecule Activated by Insulin-like Growth Factor-I, Insulin, and Interleukin-4 in Estrogen Receptor-positive Human Breast Cancer Cells

1 reference

12 December 2020

Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/565839

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

25114970

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25114970%20AND%20SRC:MED&resulttype=core&format=json