(Q35479152)

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The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling

scientific article published on 8 June 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 August 2017

The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Lewis C. Cantley

10

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Ralph Weissleder

9

object named as

Ralph Weissleder

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

11

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C Ronald Kahn

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

3

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Tatsuya Kondo

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Gregory Stephanopoulos

8

object named as

Gregory Stephanopoulos

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Cullen M. Taniguchi

1

object named as

Cullen M Taniguchi

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

author name string

Jonathon Winnay

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Roderick T Bronson

4

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Alexander R Guimaraes

5

1 reference

Europe PubMed Central

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8 August 2017

José O Alemán

6

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Europe PubMed Central

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8 August 2017

Ji Luo

7

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8 August 2017

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publication date

8 June 2010

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Europe PubMed Central

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8 August 2017

Cancer Research

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Europe PubMed Central

PubMed publication ID

8 August 2017

70

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Europe PubMed Central

PubMed publication ID

8 August 2017

13

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Europe PubMed Central

PubMed publication ID

8 August 2017

5305-5315

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Knockin of mutant PIK3CA activates multiple oncogenic pathways

1 reference

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Hepatocellular carcinoma: development and early detection

1 reference

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Understanding PTEN regulation: PIP2, polarity and protein stability

1 reference

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An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer

1 reference

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Association between phosphatidylinositol 3-kinase regulatory subunit p85alpha Met326Ile genetic polymorphism and colon cancer risk

1 reference

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Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis

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Molecular pathways and related target therapies in liver carcinoma.

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Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

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Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

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The p85alpha regulatory subunit of phosphoinositide 3-kinase potentiates c-Jun N-terminal kinase-mediated insulin resistance

1 reference

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27 July 2018

Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.

1 reference

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27 July 2018

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

1 reference

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27 July 2018

Dysregulation of growth factor signaling in human hepatocellular carcinoma.

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X chromosomal abnormalities in basal-like human breast cancer

1 reference

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Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model

1 reference

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27 July 2018

The negative regulation of phosphoinositide 3-kinase signaling by p85 and it's implication in cancer

1 reference

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27 July 2018

Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase

1 reference

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27 July 2018

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases

1 reference

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Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

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The life and death of DNA-PK.

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Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis

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Gene expression profiling identifies clinically relevant subtypes of prostate cancer

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Gene expression profile linked to p53 status in hepatitis C virus-related hepatocellular carcinoma

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Glycogen storage disease type I: pathophysiology of liver adenomas

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Gene-expression profiles predict survival of patients with lung adenocarcinoma

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Gene expression patterns in human liver cancers

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Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes

1 reference

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Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase

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Phosphorylation of the PTEN tail regulates protein stability and function

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Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

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A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes

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12 December 2020

based on heuristic

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Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess

1 reference

https://pubmed.ncbi.nlm.nih.gov/20530665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Epigenetic and genetic alterations of PTEN in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20530665

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based on heuristic

inferred from PubMed ID database lookup

The increasing incidence of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20530665

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-09-3399

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

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