(Q54346289)

28 May 2018

title

Tumour necrosis factor-α drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis. (English)

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28 May 2018

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5

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author name string

Mi Ryu

1

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28 May 2018

Shrikant R Mulay

2

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Nicolai Miosge

3

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Oliver Gross

4

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publication date

26 September 2011

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28 May 2018

published in

Journal of Pathology

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28 May 2018

volume

226

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issue

1

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28 May 2018

page(s)

120-131

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Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease

cites work

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Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy

21 January 2018

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The renal lesions of Alport syndrome

21 January 2018

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Alport's syndrome, Goodpasture's syndrome, and type IV collagen.

21 January 2018

1 reference

Interstitial inflammation in Alport syndrome

21 January 2018

1 reference

Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis

21 January 2018

1 reference

Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease

21 January 2018

1 reference

Functions of TNF and its receptors in renal disease: distinct roles in inflammatory tissue injury and immune regulation

21 January 2018

1 reference

Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease.

21 January 2018

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Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice.

21 January 2018

1 reference

Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice.

21 January 2018

1 reference

A new method for large scale isolation of kidney glomeruli from mice

21 January 2018

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Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.

21 January 2018

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The role of the podocyte in glomerulosclerosis

21 January 2018

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Regeneration of glomerular podocytes by human renal progenitors

21 January 2018

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Recruitment of podocytes from glomerular parietal epithelial cells

21 January 2018

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By homing to the kidney, activated macrophages potently exacerbate renal injury

21 January 2018

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Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes.

21 January 2018

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

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Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

21 January 2018

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Modulation of TNF receptor family members to inhibit autoimmune disease

21 January 2018

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Pretreatment with the tumor nerosis factor-alpha blocker etanercept attenuated ischemia-reperfusion renal injury.

21 January 2018

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Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury.

21 January 2018

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Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure

21 January 2018

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Suppression of nephrin expression by TNF-alpha via interfering with the cAMP-retinoic acid receptor pathway.

21 January 2018

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Testosterone and 17β-estradiol have opposite effects on podocyte apoptosis that precedes glomerulosclerosis in female estrogen receptor knockout mice

21 January 2018

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Podocyte injury induced by mesangial-derived cytokines in IgA nephropathy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.2979

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28 May 2018

PubMed ID

21953121

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28 May 2018