(Q54359599)

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Combined p53 and MDM2 biomarker analysis shows a unique pattern of expression associated with poor prognosis in patients with renal cell carcinoma undergoing radical nephrectomy.

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21756282

Combined p53 and MDM2 biomarker analysis shows a unique pattern of expression associated with poor prognosis in patients with renal cell carcinoma undergoing radical nephrectomy. (English)

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21756282

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renal cell carcinoma

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based on heuristic

inferred from title

Radical nephrectomy

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based on heuristic

inferred from title

11

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Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21756282

object named as

Aidan P Noon

1

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Radosław Polański

2

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Europe PubMed Central

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Ashraf Y El-Fert

3

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Europe PubMed Central

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Helen Kalirai

4

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Europe PubMed Central

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Howida Shawki

5

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Europe PubMed Central

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Fiona Campbell

6

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Andy Dodson

7

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http://europepmc.org/abstract/MED/21756282

Richard M Eccles

8

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Bryony H Lloyd

9

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http://europepmc.org/abstract/MED/21756282

David R Sibson

10

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http://europepmc.org/abstract/MED/21756282

Sarah L Lake

12

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Keith Parsons

13

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Nikolina Vlatković

14

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28 May 2018

http://europepmc.org/abstract/MED/21756282

Mark T Boyd

15

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http://europepmc.org/abstract/MED/21756282

publication date

14 July 2011

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BJU International

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http://europepmc.org/abstract/MED/21756282

109

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http://europepmc.org/abstract/MED/21756282

8

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28 May 2018

http://europepmc.org/abstract/MED/21756282

1250-1257

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28 May 2018

http://europepmc.org/abstract/MED/21756282

2004 WHO classification of the renal tumors of the adults

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https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Cancer statistics, 2007

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https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Targeted molecular therapy for renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

p53 and MDM2 in renal cell carcinoma: biomarkers for disease progression and future therapeutic targets?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

p53 regulation and function in renal cell carcinoma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Using protein expressions to predict survival in clear cell renal carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Molecular signatures of localized clear cell renal cell carcinoma to predict disease-free survival after nephrectomy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

p53 is an independent predictor of tumor recurrence and progression after nephrectomy in patients with localized renal cell carcinoma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Value of p53 as a prognostic marker in histologic subtypes of renal cell carcinoma: a systematic analysis of primary and metastatic tumor tissue

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

MDM2 promotes cell motility and invasiveness through a RING-finger independent mechanism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Diagnostic and prognostic molecular markers for renal cell carcinoma: a critical appraisal of the current state of research and clinical applicability

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-410X.2011.10433.X

21 January 2018

Identifiers

10.1111/J.1464-410X.2011.10433.X

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21756282

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 May 2018

http://europepmc.org/abstract/MED/21756282

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